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Annals of Intensive Care

Table 1 Results obtained during three periods of 1 hour of controlled mechanical ventilation in 13 COPD patients during the first 24 after intubation

From: Helium in the adult critical care setting

 

First period

air-oxygen

Second period

helium-oxygen

Third period

air-oxygen

Pmax, cmH2O

35.4 ± 6.7

31.6 ± 7.6*

34.9 ± 6.9

Ppl, cmH2O

22.3 ± 4.9

20.9 ± 5.5*

21.7 ± 4.7

P1 - Ppl, cmH2O

4.5 ± 2.2

4.7 ± 1.7

4.6 ± 2.3

statPEEPi, cmH2O

11.7 ± 4.0

10.3 ± 4.3*

10.9 ± 3.8

dynPEEPi, cmH2O

3.1 ± 1.0

2.7 ± 0.7*

3.0 ± 0.8

PaO2, mmHg

77 ± 12

79 ± 15

80 ± 12

PaCO2, mmHg

59 ± 12

62 ± 14

61 ± 14

VD/VT, %

71 ± 6

69 ± 5

69 ± 7

  1. Ppl = plateau pressure measured after an endinspiratory pause of 5 sec; P1 - Ppl = difference between the pressure (P1) measured after the rapid initial fall in pressure during an inspiratory pause, at the first point of zero flow, and Ppl; statPEEPi = static intrinsic PEEP; dynPEEPi = dynamic intrinsic PEEP; VD/VT = physiological dead-space
  2. Results are expressed as mean ± SD
  3. *Indicates a significant difference at the 0.05 level.
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