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Table 1 Patient characteristics

From: Retrospective evaluation of possible renal toxicity associated with continuous infusion of vancomycin in critically ill patients

Variable No AKI (n = 91) AKI (n = 38) P value
SAPS 3 67 ± 15 68 ± 14 0.63
Age, yrs 60.8 ± 14.6 62.6 ± 15.9 0.53
Weight, kg 70.5 ± 15.2 77.3 ± 15.0 0.02*
Gender, % male 51.6 60.5  
Concomitant medication    
   Aminoglycosides, n (%) 39 (43) 12 (32) 0.32
   ACEi or AT-IIra, n (%) 17 (19) 7 (18) 1
   NSAIDs, n (%) 4 (4) 1 (3) 1
   Immunosuppressants, n (%) 2 (2) 0 (0) 1
Comorbidities    
   Diabetes, n (%) 49 (54) 30 (79) 0.01*
   Shock, n (%) 54 (59) 33 (87) 0.002*
  1. AKI = acute kidney injury; SAPS = Simplified Acute Physiology Score; ACEi = angiotensin converting enzyme inhibitors; AT-IIra = angiotensin-II receptor antagonists; NSAIDs = non steroidal anti-inflammatory drugs
  2. * P level < 0,05 is considered significant
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