Table 1 Studies that have reported alterations in sublingual microcirculation in patients with severe sepsis and septic shock
From: Microcirculatory alterations: potential mechanisms and implications for therapy
Reference | No. of patients | Intervention |
|---|---|---|
De Backer et al. AJRCCM 2002 | 50 | Topical acetylcholine |
Spronk et al. Lancet 2002 | 6 | Nitroglycerin |
Sakr et al. CCM 2004 | 49 | Sequential assessment |
De Backer et al. CCM 2006 | 22 | Dobutamine |
De Backer et al. CCM 2006 | 40 | Activated protein C |
Creteur et al. ICM 2006 | 18 | Dobutamine |
Boerma et al. CCM 2007 | 23 | Sequential assessment |
Trzeciak et al. Ann Emerg Med 2007 | 26 | None |
Sakr et al. CCM 2007 | 35 | Transfusions |
Trzeciak et al. ICM 2008 | 33 | Goal directed therapy |
Boerma et al. ICM 2008 | 35 | None |
Jhanji et al. ICM 2009 | 16 | Norepinephrine |
Dubin et al. Crit Care 2009 | 20 | Norepinephrine |
Buchele et al. CCM 2009 | 20 | Hydrocortisone |
Boerma et al. CCM 2010 | 70 | Nitroglycerin |
Ospina et al. ICM 2010 | 60 | Fluids |
Spanos et al. Shock 2010 | 48 | None |
Pottecher et al. ICM 2010 | 25 | Fluids |
Morelli et al. Crit Care 2010 | 40 | Levosimendan |
Ruiz et al. Crit Care 2010 | 12 | High flow hemofiltration |
Dubin et al. J Crit Care 2010 | 20 | Fluids |
Morelli et al. ICM 2011 | 20 | Terlipressin |