Macroscopic aspect of rat lungs after mechanical ventilation at 45 cm H
O peak airway pressure. Left: normal lungs; middle: after 5 min of high airway pressure mechanical ventilation. Note the focal zones of atelectasis (in particular at the left lung apex); right: after 20 min, the lungs were markedly enlarged and congestive; edema fluid fills the tracheal cannula. Used with permission. From Dreyfuss et al. .