Table 1 Characteristics of the study groups

Age (yr)

71 (41-87)

73 (55-83)

Male gender, %

11 (52.4)

5 (45.5)

APACHE II score

24 (17-39)

25 (20-39)

SOFA score

8 (3-17)

9 (3-16)

Source of infection, %

   Lung

11 (52.4)

3 (27.3)

   Abdomen

6 (28.6)

4 (36.4)

   Urinary tract

3 (14.3)

3 (27.3)

   Line

1 (4.7)

1 (9.0)

Vasopressors/inotropes dose^c

   Norepinephrine, mcg/min

10; 10 (2-40)

6; 10 (2-25)

   Dobutamine, mcg/kg/min

4; 5 (2.5-10)

2; 3.7 (2.5-5)

Sedation/analgesic dose^c

   Midazolam, mg/hr

7; 2 (2-4)

4; 2 (2-4)

   Fentanyl, mcg/hr

8; 100 (50-400)

4; 100(50-400)

Human recombinant activated protein C, %

14.3

27.3

Renal replacement therapy, %

33.3

27.3

Red blood cell storage time (days)

32 (21-39)

32 (22-39)

In-hospital mortality, %

47.6

45.6