Hormonal changes of the HPA-axis following experimental sepsis. (A) Plasma levels obtained from healthy rats (neg ctrl) or septic littermates (6-48 hrs after CLP). (B) Plasma samples from septic animals were obtained 6-48 hrs after CLP and compared with healthy rats. (C) Aldosterone concentrations were assessed as a function of time in septic vs. healthy rats. All samples were analyzed by ELISA. n = 5-10 per experimental condition.