Efficacy and safety of recruitment maneuvers in acute respiratory distress syndrome

Annals of Intensive Care

Table 2 Summary of the comparison of sighs in the study by Steimback et al. [33]

	SI	Sighs 180/40	Sighs 10/40	Sighs 10/20
Oxygenation	↑	↑	↓	↓
Est, L	→	↓	↓	↑
Alveolar collapse	↓	↓	↓	↑
Overdistension	→	↑	↓	→
Alveolar-capillary Membrane injury	↓	↑	↓	→
Lung apoptosis	↓	↑	↓	→
mRNA PCIII	↓	↑	↓	→

SI, sustained inflation; sighs, rate per minute/target plateau pressure; Est, L, lung static elastance; mRNAPCIII, lung expression of mRAN of procollagen III.
The arrows indicate the direction of change of each variable relative to the group of injured lungs not receiving recruitment maneuvers.