| Before matching | After matching | |||||||
---|---|---|---|---|---|---|---|---|---|
Demographic or disease characteristic | VASST cohort | SPH cohort | VASST and SPH combined | ||||||
DrotAA(n = 103) | Control(n = 370) | P value | DrotAA(n = 38) | Control(n = 227) | P value | DrotAA(n = 130) | Control a (n = 286) | P value | |
Age | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Mean ± SD | 57.6 ± 15.6 | 62 ± 15.4 | 0.009 | 54.6 ±20.1 | 61 ± 14.9 | 0.072 | 58.4 ± 15.4 | 58.7 ± 15.3 | 0.886 |
Women (percentage of patients) | 35.9% | 41.4% | 0.32 | 44.7% | 33.5% | 0.178 | 40% | 36.8% | 0.596 |
APACHE II score | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Mean ± SD | 27 ± 7.4 | 0.253 | 25.7 ± 6.4 | 22.9 ± 7.2 | 0.02 | 27.1 ± 5.8 | 27 ± 5.9 | 0.862 |  |
Medical (percentage of patients) | 85.4% | 76.5% | 0.051 | 89.5% | 83.3% | 0.332 | 86.2% | 79.4% | 0.106 |
Organ failure (percentage of patients) | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Cardiovascular | 100% | 100% | 1 | 84.2% | 82.4% | 0.783 | 95.4% | 96.2% | 0.418 |
Respiratory | 85.4% | 85.4% | 0.994 | 94.7% | 93% | 0.686 | 86.9% | 86% | 0.71 |
Renal | 61.2% | 46.2% | 0.007 | 47.4% | 46.3% | 0.899 | 59.2% | 55.5% | 0.172 |
Hematologic | 23.3% | 19.5% | 0.391 | 13.2% | 13.7% | 0.934 | 19.2% | 15.1% | 0.292 |
Ventilation (percentage of patients) | 98.1% | 93.5% | 0.073 | 100% | 89.4% | 0.036 | 99.2% | 99.2% | 1 |
Caucasian (percentage of patients) | 80.6% | 83.2% | 0.528 | NA | NA | Â | NA | NA | Â |