Variables | ICU mortality | One-year mortality | |||
---|---|---|---|---|---|
Crude odds ratio | Adjusted odds ratio | Crude hazard ratio | Adjusted hazard ratio | ||
OR [95% CI] p | OR [95% CI] p | HR [95% CI] p | HR [95% CI] p | ||
HAART | |||||
No HAART at admission + no introduction in ICU | 1.00 [−] - | - | 1.00 [−] - | 1.00 [−] | |
No HAART at admission + introduction in ICU | 0.471 [0.087-2.533] 0.380 | - | 0.807 [0.277-2.355] 0.695 | 0.166 [0.043-0.642] 0.009 | |
HAART active at admission and pursued | 0.412 [0.118-1.438] 0.164 | - | 0.948 [0.446-2.014] 0.889 | 1.519 [0.519-4.444] 0.446 | |
HAART active at the admission and stopped | 1.947 [0.713-5.312] 0.193 | - | 1.827 [0.963-3.466] 0.065 | 1.758 [0.633-4.887] 0.279 | |
Introducing or pursuing HAART in ICU | 0.339 [0.123-0.937] 0.037 | 0.278 [0.082-0.939] 0.039 | 0.72 [0.39-1.33] 0.294 | - | |
Immunovirological status | |||||
CD4 T-cell count <200 /mm3 | 1.332 [0.542-3.273] 0.532 | - | 1.348 [0.73-2.489] 0.34 | - | |
HIV RNA load >1,000 copy/mL | 1.153 [0.503-2.645]- 0.737 | - | 0.935 [0.541-1.616] 0.809 | - | |
CD4high + VL low | 1.00 [−] - | - | 1.00 [−] - | 1.00 [−] - | |
Combination | CD4high + VLhigh | 2.778 [0.428-18.037] 0.857 | - | 2.736 [0.707-10.594] 0.145 | 2.344 [0.442-12.434] 0.317 |
CD4low + VLhigh | 3.000 [0.578-15.583] 0.659 | - | 2.583 [0.77-8.670] 0.124 | 5.19 [1.328-20.279] 0.018 | |
CD4low + VL low | 5.000 [0.704-35.493] 0.208 | - | 7.411 [2.02-27.195] 0.002 | 4.714 [1.178-18.867] 0.028 | |
Comorbidity | |||||
Hepatitis C virus infection | 1.83 [0.760-4.406] 0.178 | - | 1.469 [0.829-2.603] 0.1879 | 3.268 [1.29-8.278] 0.012 | |
In-ICU data | |||||
Use of vasoactive drugs | 9.762 [3.512-27.132] <0.001 | 3.779 [1.11-12.861] 0.033 | 4.2 [2.257-7.815] <0.001 | 3.68 [1.394-9.716] 0.008 | |
Mechanical ventilation | 7.529 [2.585-21.923] <0.001 | 3.317 [0.955-11.521] 0.059 | 3.139 [1.64-6.007] <0.001 | - | |
Albumin | 0.97 [0.926-1.015] 0.19 | - | 0.968 [0.937-1.001] 0.058 | - | |
Acid lactic in the first 24 h | 1.326 [1.104-1.593] 0.002 | - | 1.205 [1.109-1.31] <0.001 | - | |
SAPS II | 1.06 [1.029-1.091] <0.001 | 1.04 [1.003-1.077] 0.032 | 1.065 [1.048-1.084] <0.001 | 1.09 [1.057-1.124] <0.001 |