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Table 1 Characteristics of the ideal biomarker of infection [13, 14]

From: Biomarker-guided antibiotic therapy in adult critically ill patients: a critical review

1  Easy to use and interpret
2  Objective
3  Rapidly available
4  Reproducible
5  Good sensitivity and good specificity
6  Dynamic – rapid increases and decreases
7  Level not dependent of the underlying pathology and not modified by any treatment or intervention unless interventions related to the source control and/or antibiotic therapy
8  Continuous and not a discrete variable
9  Correlation with clinical severity and mortality
10  Prolonged and successive infections without “exhaustion” or “fatigue”
11  Inexpensive
12  Easily available