From: The transition from acute to chronic pain: might intensive care unit patients be at risk?
Acute pain | Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing [20]). Year introduced: 2012. |
Allodynia | Pain due to a stimulus that does not normally provoke pain [20]. |
Central sensitization | Increased responsiveness of nociceptive neurons in the central nervous system to their normal or subthreshold afferent input [20]. |
Chronic pain | Pain that continues or recurs over a prolonged period, caused by various diseases or abnormal conditions [28]. |
Hyperalgesia | Increased pain from a stimulus that normally provokes pain [20]. |
Hypersensitivity or hyperesthesia | Increased sensitivity to stimulation, excluding the senses [20]. |
Long-term potentiation (LTP) | A long-lasting strengthening of the response of a postsynaptic nerve cell to stimulation across the synapse that occurs with repeated stimulation and is thought to be related to learning and long-term memory [29]. |
Modulation | The inhibition or facilitation of pain [30]. |
Neuropathic pain | Pain caused by a lesion or disease of the somatosensory nervous system [20]. |
Pain affect | Feeling or emotion related to pain, especially as manifested by facial expression or body language [31]. |
Pain sensation | An unpleasant sensory experience associated with actual or potential tissue damage, or described in terms of such damage [20]. |
Peripheral sensitization | Increased responsiveness and reduced threshold of nociceptive neurons in the periphery to the stimulation of their receptive fields [32]. |
Sensitization | An increased response to stimulation that is mediated by amplification of signaling [32]. |
Supraspinal | Situated above the vertebral column [31]. |
Synaptic plasticity | The ability of the connection, or synapse, between two neurons to change in strength in response to use or disuse of transmission over synaptic pathways [33]. |