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Table 2 Hemodynamic variations and therapeutic interventions from H1 to H6

From: Benefits of an early cooling phase in continuous renal replacement therapy for ICU patients

  Group A Group B P intergroup
  Period 1 temperature 38°C Period 1 temperature 36°C  
  n = 16 n = 14  
  H1 H6 H6-H1 P Intra- group H1 H6 H6-H1 P Intra-group H6-H1
SAP mmHg 118 [26] 118 [26] 0.2 [18.9] 0.73 113 [26] 125 [20] 12.3[4.4] 0. 01 0.06
DAP mmHg 58 [13] 60 [11] 1.4 [9] 0.65 58 [9] 65 [10] 6.3 [10.6] 0.055 0.28
MAP mmHg 77 [15] 78 14] 1.2 [11.4] 0.67 71 [7] 80 [12] 8.9 [11] 0.01 0.08
HR beat/min 95 [16] 92 [18] −3 [5.9] 0.06 103 [23] 97 [28] −5.5 [28.3] 0.49 0.86
Lactates (mmol/L) 4.1 [3.4] 4.9 [4.5] 0.4 [2.2] 0.58 3.2 [2.3] 2.6 [2.0] 0.1 [0.3] 0.31 0.2
Nep dosage μg/kg/min 0.47 [1.19] 0.47 [1.33] 0.013 [0.2] 0.72 0.93 [0.81] 0.62 [0.56] −0.55 [0.3] 0.04 0.15
Increase of CA dose (no. patients) 6 4  
Decrease of CA dose (no. patients) 6 7  
Fluid infusion (no. patients) 5 2  
Total volume infused (ml) 3500 2500  
Therapeutic action (no. patients) 8 5  
  1. Values are expressed as mean [SD] or median (interquartile range); SAP systolic arterial pressure, DAP diastolic arterial pressure, MAP mean arterial pressure, Nep norepinephrine, CA catecholamine. Therapeutic intervention: fluid infusion or increase dosage of catecholamine. P intragroup: H6 vs. H1.