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Table 1 Demographics, comorbid medical conditions, presenting symptoms, vital signs, laboratory values, and acuity scores on ICU admission a

From: Relative cost and outcomes in the intensive care unit of acute lung injury (ALI) due to pandemic influenza compared with other etiologies: a single-center study

Baseline characteristics

Influenza (n = 23)

Noninfluenza (n = 22)

p value b

  Age (yr)

44 ± 13

51 ± 17

0.15

  Gender (M:F)

10:13

11:11

0.77

  BMI (kg/m2)

40 ± 22

32 ± 12

0.15

Comorbid medical conditions

  Hypertension

13

12

0.57

  Tobacco use

12

12

0.68

  Chronic renal insufficiency

1

6

0.05

  Malignancy

2

7

0.07

  Immunosuppression

4

6

0.49

  Alcohol abuse

1

6

0.05

  Ischemic heart disease

1

4

0.19

  Cirrhosis

0

4

0.05

  Prior pulmonary disease

4

7

0.31

Presenting symptoms to ICU

  Lower respiratory infection

100% (23)

73% (16)

0.135

  CNS infection

0

4.5% (1)

0.489

  Shock requiring vasopressors

22% (5)

45% (10)

0.07

Vital Signs

  SBP (mm Hg)

131 ± 23

110 ± 19

0.004

  DBP (mm Hg)

71.6 ±12

60.5 ± 10

0.004

  Temperature (°C)

37.8 ± 1.5

37 ± 1.2

0.089

  RR (breath/min)

23.4 ± 8.7

31.7 ± 21.4

0.14

  HR (beats/min)

106 ± 27.3

108 ± 18

0.81

Laboratory values

  WBC (k/μL)

10.6 ±7.46

11.4 ± 10.7

0.77

  Platelets (k/μL)

196 ± 119

138 ± 127

0.12

  Creatinine (mg/dL)

1.59 ± 1.13

1.62 ± 1.22

0.92

  Bilirubin (mg/dL)

0.65 ± 0.46

3.3 ± 8.3

0.13

  CK (U/L)

1155 ± 1642

723 ± 1551

0.45

Cause of ALI

  Pneumonia

100% (23)

41% (9)

<0.001

  Sepsis

0

23% (5)

0.02

  Aspiration

0

9% (2)

0.23

  Transfusion reaction

0

5% (1)

0.49

  Other

0

23% (5)

0.02

Acuity on ICU admission

  APACHE III score

66 ± 20 (19)

89 ± 32 (20)

0.015

  SOFA score

8.3 ± 3.4

9.2 ± 4.1

0.44

Length of stay (median ± IQR)

  ICU length of stay (days)

16 ± 22

24.5 ± 26.5

0.17c

  Hospital length of stay (days)

12 ± 15

17 ± 25.5

0.45c

  1. aValues expressed as mean ± SD unless otherwise noted; b t test or chi-squared; cWilcoxon test. CNS, central nervous system; SBP, systolic blood pressure; DBP, diastolic blood pressure; RR, respiratory rate; HR, heart rate; WBC, white blood cell; CK, creatinine kinase; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment.