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Table 1 Demographics, comorbid medical conditions, presenting symptoms, vital signs, laboratory values, and acuity scores on ICU admission a

From: Relative cost and outcomes in the intensive care unit of acute lung injury (ALI) due to pandemic influenza compared with other etiologies: a single-center study

Baseline characteristics Influenza (n = 23) Noninfluenza (n = 22) p value b
  Age (yr) 44 ± 13 51 ± 17 0.15
  Gender (M:F) 10:13 11:11 0.77
  BMI (kg/m2) 40 ± 22 32 ± 12 0.15
Comorbid medical conditions
  Hypertension 13 12 0.57
  Tobacco use 12 12 0.68
  Chronic renal insufficiency 1 6 0.05
  Malignancy 2 7 0.07
  Immunosuppression 4 6 0.49
  Alcohol abuse 1 6 0.05
  Ischemic heart disease 1 4 0.19
  Cirrhosis 0 4 0.05
  Prior pulmonary disease 4 7 0.31
Presenting symptoms to ICU
  Lower respiratory infection 100% (23) 73% (16) 0.135
  CNS infection 0 4.5% (1) 0.489
  Shock requiring vasopressors 22% (5) 45% (10) 0.07
Vital Signs
  SBP (mm Hg) 131 ± 23 110 ± 19 0.004
  DBP (mm Hg) 71.6 ±12 60.5 ± 10 0.004
  Temperature (°C) 37.8 ± 1.5 37 ± 1.2 0.089
  RR (breath/min) 23.4 ± 8.7 31.7 ± 21.4 0.14
  HR (beats/min) 106 ± 27.3 108 ± 18 0.81
Laboratory values
  WBC (k/μL) 10.6 ±7.46 11.4 ± 10.7 0.77
  Platelets (k/μL) 196 ± 119 138 ± 127 0.12
  Creatinine (mg/dL) 1.59 ± 1.13 1.62 ± 1.22 0.92
  Bilirubin (mg/dL) 0.65 ± 0.46 3.3 ± 8.3 0.13
  CK (U/L) 1155 ± 1642 723 ± 1551 0.45
Cause of ALI
  Pneumonia 100% (23) 41% (9) <0.001
  Sepsis 0 23% (5) 0.02
  Aspiration 0 9% (2) 0.23
  Transfusion reaction 0 5% (1) 0.49
  Other 0 23% (5) 0.02
Acuity on ICU admission
  APACHE III score 66 ± 20 (19) 89 ± 32 (20) 0.015
  SOFA score 8.3 ± 3.4 9.2 ± 4.1 0.44
Length of stay (median ± IQR)
  ICU length of stay (days) 16 ± 22 24.5 ± 26.5 0.17c
  Hospital length of stay (days) 12 ± 15 17 ± 25.5 0.45c
  1. aValues expressed as mean ± SD unless otherwise noted; b t test or chi-squared; cWilcoxon test. CNS, central nervous system; SBP, systolic blood pressure; DBP, diastolic blood pressure; RR, respiratory rate; HR, heart rate; WBC, white blood cell; CK, creatinine kinase; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment.