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Table 1 Characteristics of all patients managed with NIV according to age

From: Results of noninvasive ventilation in very old patients

 

Patients ≥ 80 y (n = 98)

Patients < 80 y (n = 278)

p value

Characteristics at ICU admission

   

Age, yr

84 (80-86)

67 (54-74)

< 0.001

[min-max]

[80-94]

[17-79]

 

Gender, M/F, n

45/53

185/93

< 0.001

Home respiratory support, n (%)

14 (14)

28 (10)

0.4

   Nasal O2

10

17

 

   NIV

4

11

 

History of ICU admission for ARF, n (%)

18 (18)

49 (18)

0.87

Immunocompromised, n (%)a

9 (9)

54 (19)

0.02

Location before ICU admission, n (%)

  

0.15

   Emergency room

59 (60)

140 (50)

 

   Medical ward

28 (29)

110 (40)

 

   Surgical ward

11 (11)

28 (10)

 

NIV start before ICU admission, n (%)

15 (15)

28 (10)

0.16

SAPS II at admission, points

43 (36-52)

39 (31-49)

< 0.01

Non-age-related SAPS II, pointsb

25 (18-34)

27 (20-38)

0.21

Characteristics at NIV start

   

Patients with extra respiratory organ failure, n (%)c

65 (66)

189 (68)

0.76

NIV context, n (%)

  

< 0.001

   CPE-AOC respiratory failure

30 (31)

93 (34)

 

   de novo ARF

16 (16)

79 (28)

 

   Postextubation

13 (13)

84 (30)

 

   Do-not-intubate order

39 (40)

22 (8)

 

ABG before NIV start

   

   pH

7.35 (7.27-7.42)

7.38 (7.30-7.44)

0.05

   PaCO2, mmHg

57 (40-71)

47 (37-60)

< 0.01

   PaO2/FiO2, mmHg

189 (145-235)

190 (120-240)

0.69

NIV management

   

NIV duration within the first 24 hours, h

6 (4-10)

4 (3-8)

< 0.001

Period of NIV delivery during ICU stay, d

3 (1-5)

2 (1-3)

< 0.001

Discharged from ICU with NIV, n (%)d

9/94 (10)

11/267 (4)

0.05

  1. ABG, arterial blood gases; ARF, acute respiratory failure; CPE-AOC, cardiogenic pulmonary edema and acute-on-chronic respiratory failure; ICU, intensive care unit; NIV, noninvasive ventilation. aAIDS, neutropenia < 500/mm3, immune-suppressive drugs, chemotherapy, long-term, or recent high dose of steroids. bSimplified Acute Physiology Score (SAPS II) minus points for age. cAt least one point in the nonrespiratory SOFA score. dIn patients without NIV home treatment before ICU admission.