From: Results of noninvasive ventilation in very old patients
 | Patients ≥ 80 y (n = 98) | Patients < 80 y (n = 278) | p value |
---|---|---|---|
Characteristics at ICU admission | Â | Â | Â |
Age, yr | 84 (80-86) | 67 (54-74) | < 0.001 |
[min-max] | [80-94] | [17-79] | Â |
Gender, M/F, n | 45/53 | 185/93 | < 0.001 |
Home respiratory support, n (%) | 14 (14) | 28 (10) | 0.4 |
   Nasal O2 | 10 | 17 |  |
   NIV | 4 | 11 |  |
History of ICU admission for ARF, n (%) | 18 (18) | 49 (18) | 0.87 |
Immunocompromised, n (%)a | 9 (9) | 54 (19) | 0.02 |
Location before ICU admission, n (%) | Â | Â | 0.15 |
   Emergency room | 59 (60) | 140 (50) |  |
   Medical ward | 28 (29) | 110 (40) |  |
   Surgical ward | 11 (11) | 28 (10) |  |
NIV start before ICU admission, n (%) | 15 (15) | 28 (10) | 0.16 |
SAPS II at admission, points | 43 (36-52) | 39 (31-49) | < 0.01 |
Non-age-related SAPS II, pointsb | 25 (18-34) | 27 (20-38) | 0.21 |
Characteristics at NIV start | Â | Â | Â |
Patients with extra respiratory organ failure, n (%)c | 65 (66) | 189 (68) | 0.76 |
NIV context, n (%) | Â | Â | < 0.001 |
   CPE-AOC respiratory failure | 30 (31) | 93 (34) |  |
   de novo ARF | 16 (16) | 79 (28) |  |
   Postextubation | 13 (13) | 84 (30) |  |
   Do-not-intubate order | 39 (40) | 22 (8) |  |
ABG before NIV start | Â | Â | Â |
   pH | 7.35 (7.27-7.42) | 7.38 (7.30-7.44) | 0.05 |
   PaCO2, mmHg | 57 (40-71) | 47 (37-60) | < 0.01 |
   PaO2/FiO2, mmHg | 189 (145-235) | 190 (120-240) | 0.69 |
NIV management | Â | Â | Â |
NIV duration within the first 24 hours, h | 6 (4-10) | 4 (3-8) | < 0.001 |
Period of NIV delivery during ICU stay, d | 3 (1-5) | 2 (1-3) | < 0.001 |
Discharged from ICU with NIV, n (%)d | 9/94 (10) | 11/267 (4) | 0.05 |