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Table 1 Characteristics of all patients managed with NIV according to age

From: Results of noninvasive ventilation in very old patients

  Patients ≥ 80 y (n = 98) Patients < 80 y (n = 278) p value
Characteristics at ICU admission    
Age, yr 84 (80-86) 67 (54-74) < 0.001
[min-max] [80-94] [17-79]  
Gender, M/F, n 45/53 185/93 < 0.001
Home respiratory support, n (%) 14 (14) 28 (10) 0.4
   Nasal O2 10 17  
   NIV 4 11  
History of ICU admission for ARF, n (%) 18 (18) 49 (18) 0.87
Immunocompromised, n (%)a 9 (9) 54 (19) 0.02
Location before ICU admission, n (%)    0.15
   Emergency room 59 (60) 140 (50)  
   Medical ward 28 (29) 110 (40)  
   Surgical ward 11 (11) 28 (10)  
NIV start before ICU admission, n (%) 15 (15) 28 (10) 0.16
SAPS II at admission, points 43 (36-52) 39 (31-49) < 0.01
Non-age-related SAPS II, pointsb 25 (18-34) 27 (20-38) 0.21
Characteristics at NIV start    
Patients with extra respiratory organ failure, n (%)c 65 (66) 189 (68) 0.76
NIV context, n (%)    < 0.001
   CPE-AOC respiratory failure 30 (31) 93 (34)  
   de novo ARF 16 (16) 79 (28)  
   Postextubation 13 (13) 84 (30)  
   Do-not-intubate order 39 (40) 22 (8)  
ABG before NIV start    
   pH 7.35 (7.27-7.42) 7.38 (7.30-7.44) 0.05
   PaCO2, mmHg 57 (40-71) 47 (37-60) < 0.01
   PaO2/FiO2, mmHg 189 (145-235) 190 (120-240) 0.69
NIV management    
NIV duration within the first 24 hours, h 6 (4-10) 4 (3-8) < 0.001
Period of NIV delivery during ICU stay, d 3 (1-5) 2 (1-3) < 0.001
Discharged from ICU with NIV, n (%)d 9/94 (10) 11/267 (4) 0.05
  1. ABG, arterial blood gases; ARF, acute respiratory failure; CPE-AOC, cardiogenic pulmonary edema and acute-on-chronic respiratory failure; ICU, intensive care unit; NIV, noninvasive ventilation. aAIDS, neutropenia < 500/mm3, immune-suppressive drugs, chemotherapy, long-term, or recent high dose of steroids. bSimplified Acute Physiology Score (SAPS II) minus points for age. cAt least one point in the nonrespiratory SOFA score. dIn patients without NIV home treatment before ICU admission.