Table 4 Characteristics of very old patients according to do-not-intubate (DNI) status
From: Results of noninvasive ventilation in very old patients
| Â | Very old patients without DNI order (n = 59) | Very old patients With DNI order (n = 39) | p value |
|---|---|---|---|
Decision of limitation | Â | Â | NA |
Do not intubate | 0 | 33 | Â |
Do not reintubate after extubation failure | 0 | 6 | Â |
Age (yr) | 84 (81-85) | 86 (83-89) | <0.01 |
Sex Male, n (%) | 27 (46) | 18 (46) | 0.97 |
Patients living at home before hospital admission, n (%) | 54 (92) | 32 (82) | 0.16 |
Charlson comorbidity index, n (%) | Â | Â | 0.01 |
No or low comorbidities (0-1 point) | 28 (47) | 8 (21) | Â |
High comorbidities (> 1 points) | 31 (53) | 31 (79) | Â |
Type of comorbidities | Â | Â | Â |
Dementia | 1 (2) | 6 (15) | 0.02 |
Full dependency for ADL | 0 | 11 (28) | <0.001 |
End-stage respiratory failure | 4 (7) | 16 (41) | <0.001 |
with home respiratory support | 4 | 10 | 0.016 |
Active cancer | 7 (12) | 4 (10) | 0.99 |
Chronic heart failure | 24 (41) | 17 (44) | 0.77 |
Peripheral obstructive arterial disease | 5 (8) | 6 (15) | 0.34 |
SAPS II, points | 43 (36-52) | 43 (36-50) | 0.75 |
Patients with extra-respiratory OF a , n (%) | 38 (64) | 27 (69) | 0.67 |
ABG before NIV start | Â | Â | Â |
pH | 7.36 (7.27-7.43) | 7.32 (7.22-7.4) | 0.18 |
PaCO2 (mmHg) | 46 (38-64) | 67 (53-80) | <0.01 |
PaO2/FiO2 ratio (mmHg) | 180 (120-268) | 195 (168-216) | 0.59 |
NIV delivery | Â | Â | Â |
Within first 24 hours (h) | 6 (4-8) | 9 (6-15) | <0.001 |
During ICU stay (d) | 2 (1-3) | 4 (3-6) | <0.001 |
Continuing need for NIV on day 6, n (%) | 3 (5) | 12 (33) | 0.011 |
ICU length of stay (d) | 8 (5-13) | 8 (5-14) | 0.87 |
Among survivors | 8 (5-13) | 7 (5-14) | 0.48 |
Hospital length of stay (d) | 25 (13-40) | 20 (8-37) | 0.21 |
Among survivors | 27 (17-40) | 29 (17-45) | 0.25 |