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Table 1 Risk factors for Invasive Candida Infection in children (from [3])

From: Invasive fungal disease in PICU: epidemiology and risk factors

Risk factors for invasive candidiasis Unadjusted odds ratio 95% Confidence interval
Malignancy 3.22 1.36-7.6
Presence of a central venous catheter 13.4 4.8-37.42
Presence of a arterial catheter 1.77 1.02-3.06
Receipt of total parenteral nutrition 5.3 2.8-10.05
Neutropenia within 15 days 5.58 1.12-27.79
Non-candidal blood stream infection within 15 days 2.47 1.35-4.52
Receipt of antifungal agents within 15 days 2.86 1.44-5.66
Receipt of antibiotics within 15 days 5.44 1.87-15.77
Parenteral or oral vancomycin during 1-3 days 2.56 1.27-5.16
Parenteral or oral vancomycin ≥4 days 3.17 1.73-5.82
Extended-spectrum cephalosporins ≥4 days 2.31 1.26-4.22
Carbapenems ≥4 days 3.29 1.1-9.89
Aminoglycosides 2.09 1.17-3.74
Agents covering anaerobic organisms ≥4 daysa 2.3 1.29-4.11
  1. aIncluding ampicillin sulbactam, clindamycin, imipenem, meropenem, metronidazole, and ticarcillin-clavulanate