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Table 3 Predictive performance for detecting fluid responsiveness

From: Non-invasive assessment of fluid responsiveness by changes in partial end-tidal CO2 pressure during a passive leg-raising maneuver

  Threshold Sensitivity Specificity PV + PV - LR + LR -
ΔCO PLR 12% 95.2% 93.7% 95.2% 93.7% 15.24 .05
[95% CI]   [76.2-99.9%] [69.8-99.8%] [75.5-99.9%] [69.8-99.8%] [13-17.9] [0.003-0.8]
ΔPETCO 2-PLR 5% 90.5% 93.7% 95% 88.2% 14.48 .1
[95% CI]   [69.6-98.8%] [69.8-99.8%] [75.1-99.9%] [62.6-98.7%] [12-17.5] [0.01-1]
FTc 300 ms 66.7% 81.2% 82.4% 65% 3.56 .41
[95% CI]   [43-85.4%] [54.4-96%] [55.6-96.5%] [40.8-84.6%] [2.4-5.2] [0.1-1.3]
ΔPP PLR 11% 66.7% 81.2% 82.4% 65% 3.56 .41
[95% CI]   [43-85.4%] [54.4-96%] [55.6-96.5%] [40.8-84.6%] [2.4-5.2] [0.1-1.3]
  1. ΔCOPLR, passive leg raising induced-change in cardiac output; ΔPETCO2-PLR, passive leg raising-induced change in partial end-tidal CO2;, ΔPP-PLR, passive leg raising-induced change in arterial pulse pressure; FTc, aortic blood flow corrected time; PV+, positive predictive value; PV -, negative predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio
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