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Table 1 Physiological parameters.

From: Temporal differences in the development of organ dysfunction based on two different approaches to induce experimental intra-abdominal hypertension in swine

Parameter Group T= 0 h (baseline)a T= 12 ha P valueb
IBP (mmHg) Control 5 (2) 7 (1) < 0.0001
  CO2 5 (2) 26 (1)c  
  VOL 5 (1) 21 (4)  
Survival (%) Control 100 100  
  CO2 100 63  
  VOL 100 63  
pCO2 (kPa) Control 4.6 (0.6) 5.4 (0.9) < 0.0001
  CO2 4.9 (0.4) 11.5 (3.2)c  
  VOL 4.5 (0.5) 7.4 (4.5)  
pH Control 7.5 (0.1) 7.5 (0.1) < 0.0001
  CO2 7.5 (0.0) 7.1 (0.1)c  
  VOL 7.6 (0.0) 7.3 (0.2)  
Base excess (mmol/l) Control 7.0 (0.8) 4.4 (1.3) < 0.0001
  CO2 7.0 (1.2) -1.4 (4.7)c  
  VOL 7.5 (1.3) -0.1 (4.6)  
Creatinine (mg/dl) Control 1.4 (0.3) 1.9 (0.5) < 0.0001
  CO2 1.4 (0.3) 3.8 (0.7)c  
  VOL 1.3 (0.3) 4.3 (0.8)c  
Diuresis (ml/h) Control 48 (38) 38 (22) 0.0005
  CO2 43 (24) 1 (2)c  
  VOL 49 (27) 4 (4)c  
K+ (mmol/l) Control 4.7 (1.0) 4.6 (0.5) < 0.0001
  CO2 4.4 (0.5) 7.6 (1.1)c  
  VOL 4.1 (0.3) 8.2 (0.4)c  
Lactate (mmol/l) Control 1.0 (0.3) 0.8 (0.4) 0.0007
  CO2 0.9 (0.2) 3.6 (3.1)  
  VOL 1.1 (0.4) 3.1 (3.3)c  
  1. aData presented as mean ± standard deviation [SD]. Control, control group; CO2, group with CO2 pneumoperitoneum; VOL, group with intra-abdominal volume addition by placement of saline bags. Statistics: group-time interactions were analyzed by repeated measures ANOVA. bDifference between groups over time. Kruskal-Wallis one-way ANOVA on ranks using Dunn's method for multiple comparisons between groups at corresponding moments, cdifferent from control,. For survival, no statistically significant different odds ratios were observed: control vs. VOL = 10.8 (P = 0.14), control vs. CO2 = 6.5 (P = 0.25), VOL vs. CO2 = 1.8 (P = 0.59). IBP, intra-bladder pressure; pCO2, partial pressure of CO2.