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Annals of Intensive Care

Table 2 Hemodynamic and pulmonary parameters.

From: Temporal differences in the development of organ dysfunction based on two different approaches to induce experimental intra-abdominal hypertension in swine

Parameter

Group

T= 0 h (baseline)a

T= 12 ha

P valueb

Heart rate (beats/min)

Control

71 (13)

92 (28)

< 0.0001

 

CO2

81 (23)

140 (35)

 
 

VOL

65 (10)

91 (14)

 

CVP (mmHg)

Control

3 (2)

5 (3)

< 0.0001

 

CO2

2 (3)

9 (2)

 
 

VOL

5 (3)

16 (7)c

 

MPAP (mmHg)

Control

11 (4)

17 (6)

0.0195

 

CO2

12 (3)

27 (10)

 
 

VOL

13 (3)

27 (9)

 

MAP (mmHg)

Control

59 (10)

60 (3)

0.0012

 

CO2

58 (11)

57 (5)

 
 

VOL

68 (12)

56 (11)

 

APP (mmHg)

Control

53 (9)

55 (4)

< 0.0001

 

CO2

54 (11)

31 (6)c

 
 

VOL

64 (12)

39 (3)c

 

Cdyn (ml/cm H2O)

Control

33 (4)

26 (5)

< 0.0001

 

CO2

33 (5)

8 (2)c

 
 

VOL

34 (2)

12 (4)c

 
  1. aData presented as mean ± SD. Control, control group; CO2, group with CO2 pneumoperitoneum; VOL, group with intra-abdominal volume addition by placement of saline bags. Statistics: group-time interactions were analyzed by repeated measures ANOVA. b P value, difference between groups over time. Kruskal-Wallis one-way ANOVA on ranks using Dunn's method for multiple comparisons between groups at corresponding moments, cdifferent from control, CVP, central venous pressure; MPAP, mean pulmonary artery pressure; MAP, mean arterial pressure; APP, abdominal perfusion pressure; Cdyn, dynamic lung compliance.
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