Influence of two different levels of intra-abdominal hypertension on bacterial translocation in a porcine model

Annals of Intensive Care

Table 4 Results of MAP and associated parameters at intervals of 6 h

Parameter	Group	0 h	6 h	12 h	18 h	24 h	Unit
MAP^{ab, c},	IAP-30^bc,	72.6 ± 8.1^bc,	70.8 ± 18.7^bc,	60.8 ± 17.8^bc,	52.9 ± 12.1^c	45.0 ± 14.6^bc,	mmHg^bc,
	IAP-15^bc,	75.2 ± 14.5^bc,	77.1 ± 9.8^bc,	88.7 ± 10.2^bc,	91.8 ± 18.7^bc,	90.5 ± 17.3^b	mmHg^bc,
	Control^bc,	71.5 ± 12.9^bc,	70.1 ± 7.7^bc,	80.4 ± 14.1^bc,	82.7 ± 8.0^bc,	83.6 ± 10.2^bc,	mmHg^bc,
APP^a = MAP - IAP	IAP-30^bc,	67.4 ± 8.3	58.3 ± 11.0	49.3 ± 18.3^bc,	43.3 ± 17.1^bc,	32.5 ± 16.5^bc,	mmHg^bc,
	IAP-15^bc,	70.5 ± 13.8	69.4 ± 8.0	78.8 ± 10.1	79.7 ± 12.1	80.8 ± 16.8	mmHg^bc,
	Control^bc,	67.0 ± 14.0	67.0 ± 7.1	78.5 ± 13.8	80.1 ± 10.5	80.4 ± 10.2	mmHg^bc,
RFG^a = MAP - 2·IAP	IAP-30^bc,	72.6 ± 8.1	13.0 ± 9.6^bc,	7.8 ± 7.2^bc,	4.6 ± 6.6^bc,	0.0 ± 0.0^bc,	mmHg^bc,
	IAP-15^bc,	75.2 ± 14.5	47.7 ± 8.1^bc,	58.7 ± 10.2^bc,	62.4 ± 16.4^bc,	60.5 ± 17.3^bc,	mmHg^bc,
	Control	71.5 ± 12.9	70.1 ± 8.0	80.4 ± 14.1	82.8 ± 9.9	83.6 ± 10.2	mmHg^bc,

^aSignificant change during 24 h according to ANOVA and post-hoc analysis: MAP (P = 0.037); APP (P = 0.002); RFG (P = 0.001). ^bSignificant difference from baseline according to paired t test: MAP (IAP-30, 24 h: P = 0.014 and IAP-15, 24 h: P = 0.010); APP (IAP-30, 12 h: P = 0.026); RFG (IAP-30, 6 h: P = 0.007 and IAP-15, 6 h: P = 0.046). ^cSignificant difference from corresponding control according to unpaired t test: MAP (IAP-30, 18 h: P = 0.004); APP (IAP-30, 12 h: P = 0.001); RFG (IAP-30, 6 h: P = 0.003 and IAP-15, 6 h: P = 0.011). IAP-15/IAP-30: animals exposed to an IAP of 15 mmHg or 30 mmHg, respectively, lasting for 24 h (each group consisting of six animals).