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Table 5 Results of blood gas analyses at intervals of 6 h

From: Influence of two different levels of intra-abdominal hypertension on bacterial translocation in a porcine model

Parameter

Group

0 h

6 h

12 h

18 h

24 h

Unit

pHab,

IAP-30ab,

7.40 ± 0.07

7.38 ± 0.04

7.31 ± 0.09

7.28 ± 0.10

7.22 ± 0.13ab,

 
 

IAP-15ab,

7.43 ± 0.05

7.36 ± 0.10

7.47 ± 0.04

7.47 ± 0.05

7.46 ± 0.04

 
 

Controlab,

7.45 ± 0.09

7.45 ± 0.07

7.51 ± 0.04

7.48 ± 0.07

7.48 ± 0.05

 

BEc

IAP-30ab,

1.1 ± 4.3

-0.8 ± 2.5

-5.6 ± 6.8

-6.8 ± 5.9ab,

-10.4 ± 4.6ab,

mmol·L-1ab,

 

IAP-15ab,

-0.5 ± 4.1

-2.1 ± 3.8

3.0 ± 1.9

2.2 ± 2.9

1.1 ± 2.7

mmol·L-1ab,

 

Controlab,

1.8 ± 2.3

3.2 ± 3.0

4.9 ± 1.4

3.6 ± 2.0

3.7 ± 1.2

mmol·L-1ab,

PO2

IAP-30ab,

137.3 ± 30.8

124.7 ± 11.1

121.27 ± 23.5

116.0 ± 18.3

105.2 ± 31.0

mmHgab,

 

IAP-15ab,

144.9 ± 17.1

141.2 ± 18.7

132.8 ± 9.7

135.6 ± 37.1

117.3 ± 40.1

mmHgab,

 

Controlab,

131.5 ± 20.8

142.9 ± 23.1

128.5 ± 18.2

146.6 ± 32.7

130.4 ± 14.2

mmHgab,

PCO2

IAP-30ab,

41.6 ± 3.6

41.9 ± 4.5

37.2 ± 10.2

33.2 ± 11.9

31.1 ± 13.4

mmHgab,

 

IAP-15ab,

35.5 ± 3.8

38.8 ± 5.9

37.6 ± 2.9

35.4 ± 4.9

34.6 ± 4.9

mmHgab,

 

Control

38.4 ± 5.8

36.9 ± 7.0

36.7 ± 4.4

36.3 ± 7.5

37.1 ± 5.2

mmHgab,

  1. aSignificant difference from baseline according to paired t test: pH (IAP-30, 24 h: P = 0.017); BE (IAP-30, 18 h: P = 0.025). bSignificant difference from corresponding control according to unpaired t test: pH (IAP-30, 18 h: P = 0.005); BE (IAP-30, 18 h: P = 0.036). cSignificant change during 24 h according to ANOVA and post-hoc analysis: BE (P = 0.019). IAP-15/IAP-30: animals exposed to an IAP of 15 mmHg or 30 mmHg, respectively, lasting for 24 h (each group consisting of six animals).