Table 2 Characteristics of group I and group II
From: Intra-abdominal hypertension in patients with sellar region tumors
Whole group | Group I (no IAH) | Group II (IAH) | p Value (significance of difference between groups I and II) | |
|---|---|---|---|---|
Number (patients) | 41 | 13 | 28 | |
Sex (male/female) | 19:22 | 8:5 | 11:17 | 0.2 |
Age (mean ± SD) | 48.3 ± 15 | 46.3 ± 17.7 | 49.3 ± 13.8 | 0.8 |
APACHE-II (mean ± SD) | 13 ± 5.6 | 9.1 ± 6.1 | 14.9 ± 4.4 | 0.0004* |
SOFA score (mean ± SD) | 2.5 ± 1.8 | 1.9 ± 2.3 | 2.7 ± 1.6 | 0.2 |
Neurosurgical pathology (patients) | ||||
Pituitary adenoma | 18 | 6 | 12 | 0.8 |
Craniopharyngioma | 11 | 1 | 10 | 0.06 |
Sellar region meningioma | 8 | 3 | 5 | 0.7 |
III ventricular glioma | 3 | 2 | 1 | 0.2 |
III ventricular ganglioma | 1 | 1 | 0 | 0.1 |
Admission value of IAP (mmHg, mean ± SD) | 9.2 ± 4.0 | 6.5 ± 3.1 | 10.6 ± 3.9 | 0.003* |
Mean value of IAP mmHg (mean ± SD) | 9.3 ± 3.1 | 6.4 ± 2.0 | 10.7 ± 2.5 | 0.000003* |
Maximal value of IAP (mmHg, mean ± SD) | 15.2 ± 6.2 | 8.9 ± 2.3 | 18.6 ± 5.6 | 0.002* |
Minimal value of APP (mmHg, mean ± SD) | 79.0 ± 9.0 | 86.5 ± 5.8 | 75.6 ± 8.2 | 0.0001* |
Risk factors for IAH (patients (%)) | ||||
Positive fluid balance | 7 (17.1) | 1 (7.7) | 6 (21.4) | 0.3 |
Acidosis | 2 (4.9 | 0 (0) | 2 (7.1) | 0.3 |
Hypothermia | 4 (9.8) | 1 (7.7) | 3 (10.7) | 0.7 |
Coagulopathy | 6 (14.6) | 1 (7.7) | 5 (17.9) | 0.4 |
MOD | 26 (63.4) | 3 (23.1) | 23 (82) | 0.0003* |
MV | 24 (58.5) | 6 (46.2) | 18 (64.3) | 0.3 |
Ileus | 34 (82.9) | 6 (46.2) | 28 (100) | 0.0001* |
Type of ileus (patients (%)) | ||||
Impaired gastric emptying | - | - | - | |
Impaired intestinal and colonic emptying | 21 (51.2) | 4 (30.8) | 17 (60.7) | 0.07 |
Combined form | 13 (31.7) | 2 (15.4) | 11 (39.3) | 0.1 |
Onset time of ileus (postoperative day) | 2.3 ± 1.4 | 1.7 ± 0.5 | 2.4 ± 1.5 | 0.17 |
Duration of ileus (days) | 10.6 ± 7.6 | 4.3 ± 1.0 | 11.9 ± 7.7 | 0.01* |
Risk factors of ileus (patients (%)) | ||||
DD | 33 (80.5) | 6 (46.2) | 27 (96.4) | 0.0002* |
Independent risk factors (patients (%)) | ||||
Narcotics | 2 (4.9) | 0 (0) | 2 (7.1) | 0.3 |
Sympathomimetics | 7 (17.1) | 5 (38.5) | 2 (7.1) | 0.01* |
Positive fluid balance | 7 (17.1) | 1 (7.7) | 6 (21.4) | 0.3 |
Sepsis | 8 (19.5) | 0 (0) | 8 (28.6) | 0.03* |
Hypokalemia, hypomagnesaemia | 28 (68.3) | 8 (61.5) | 20 (71.4) | 0.5 |
LOS (days, mean ± SD) | 18.5 ± 22.8 | 6.5 ± 4.6 | 24.1 ± 25.7 | 0.02* |
Outcome (patients (%)) | ||||
Favorable outcome GOS 4 | 26 (63.4) | 11 (85) | 15 (54) | 0.06 |
Unfavorable outcome | 15 (36.6) | 2 (15) | 13 (46) | 0.06 |
GOS 2,3 | 4 (9.8) | 0 (0) | 4 (14) | |
GOS 1 | 11 (26.8) | 2 (15) | 9 (32) |