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Table 2 Characteristics of group I and group II

From: Intra-abdominal hypertension in patients with sellar region tumors

  Whole group Group I (no IAH) Group II (IAH) p Value (significance of difference between groups I and II)
Number (patients) 41 13 28  
Sex (male/female) 19:22 8:5 11:17 0.2
Age (mean ± SD) 48.3 ± 15 46.3 ± 17.7 49.3 ± 13.8 0.8
APACHE-II (mean ± SD) 13 ± 5.6 9.1 ± 6.1 14.9 ± 4.4 0.0004*
SOFA score (mean ± SD) 2.5 ± 1.8 1.9 ± 2.3 2.7 ± 1.6 0.2
Neurosurgical pathology (patients)     
   Pituitary adenoma 18 6 12 0.8
   Craniopharyngioma 11 1 10 0.06
   Sellar region meningioma 8 3 5 0.7
   III ventricular glioma 3 2 1 0.2
   III ventricular ganglioma 1 1 0 0.1
Admission value of IAP (mmHg, mean ± SD) 9.2 ± 4.0 6.5 ± 3.1 10.6 ± 3.9 0.003*
Mean value of IAP mmHg (mean ± SD) 9.3 ± 3.1 6.4 ± 2.0 10.7 ± 2.5 0.000003*
Maximal value of IAP (mmHg, mean ± SD) 15.2 ± 6.2 8.9 ± 2.3 18.6 ± 5.6 0.002*
Minimal value of APP (mmHg, mean ± SD) 79.0 ± 9.0 86.5 ± 5.8 75.6 ± 8.2 0.0001*
Risk factors for IAH (patients (%))     
   Positive fluid balance 7 (17.1) 1 (7.7) 6 (21.4) 0.3
   Acidosis 2 (4.9 0 (0) 2 (7.1) 0.3
   Hypothermia 4 (9.8) 1 (7.7) 3 (10.7) 0.7
   Coagulopathy 6 (14.6) 1 (7.7) 5 (17.9) 0.4
   MOD 26 (63.4) 3 (23.1) 23 (82) 0.0003*
   MV 24 (58.5) 6 (46.2) 18 (64.3) 0.3
   Ileus 34 (82.9) 6 (46.2) 28 (100) 0.0001*
Type of ileus (patients (%))     
   Impaired gastric emptying - - -  
   Impaired intestinal and colonic emptying 21 (51.2) 4 (30.8) 17 (60.7) 0.07
   Combined form 13 (31.7) 2 (15.4) 11 (39.3) 0.1
Onset time of ileus (postoperative day) 2.3 ± 1.4 1.7 ± 0.5 2.4 ± 1.5 0.17
   Duration of ileus (days) 10.6 ± 7.6 4.3 ± 1.0 11.9 ± 7.7 0.01*
Risk factors of ileus (patients (%))     
   DD 33 (80.5) 6 (46.2) 27 (96.4) 0.0002*
Independent risk factors (patients (%))     
   Narcotics 2 (4.9) 0 (0) 2 (7.1) 0.3
   Sympathomimetics 7 (17.1) 5 (38.5) 2 (7.1) 0.01*
   Positive fluid balance 7 (17.1) 1 (7.7) 6 (21.4) 0.3
   Sepsis 8 (19.5) 0 (0) 8 (28.6) 0.03*
   Hypokalemia, hypomagnesaemia 28 (68.3) 8 (61.5) 20 (71.4) 0.5
LOS (days, mean ± SD) 18.5 ± 22.8 6.5 ± 4.6 24.1 ± 25.7 0.02*
Outcome (patients (%))     
   Favorable outcome GOS 4 26 (63.4) 11 (85) 15 (54) 0.06
   Unfavorable outcome 15 (36.6) 2 (15) 13 (46) 0.06
   GOS 2,3 4 (9.8) 0 (0) 4 (14)  
   GOS 1 11 (26.8) 2 (15) 9 (32)  
  1. *Significant difference. IAH, intra-abdominal hypertension; SD, standard deviation; APACHE-II, acute physiology and chronic health evaluation, and SOFA, sequential organ failure assessment, scores on ICU admission; IAP, intra-abdominal pressure; APP, abdominal perfusion pressure; MOD, multiple organ dysfunction; MV, mechanical ventilation; GOS, Glasgow Outcome Scale; LOS, length of stay.