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Table 3 Stepwise multivariate logistic regression analysis for three outcomes: mortality in the ICU, hospital and need for RRT.

From: Intra-abdominal pressure and abdominal perfusion pressure in cirrhotic patients with septic shock

Variable Intra-abdominal hypertension Variable Abdominal hypoperfusion
  Odds ratio 95% Confidence interval   Odds ratio 95% Confidence interval
ICU mortality
Intra-abdominal hypertension 12.20 1.92 to 77.31 Abdominal hypoperfusion 2.86 0.74 to 11.11
Age 1.02 0.97 to 1.08 Age 0.98 0.92 to 1.04
INR 3.60 1.29 to 10.06 INR 2.67 1.02 to 7.00
    APACHE II score 1.14 1.02 to 1.26
Hospital mortality
Intra-abdominal hypertension 6.83 0.86 to 54.12 Abdominal hypoperfusion 2.44 0.38 to 6.67
Age 1.07 0.99 to 1.17 Age 1.05 0.97 to 1.14
INR 6.2 1.07 to 38.5 INR 6.36 0.92 to 44.22
    APACHE II score 1.11 0.98 to 1.26
Renal replacement therapy
Intra-abdominal hypertension 6.78 1.29 to 35.70 Abdominal hypoperfusion 2.78 0.68 to 11.11
Age 0.92 0.92 to 1.04 Age 0.96 0.90 to 1.02
INR 2.06 0.98 to 4.32 APACHE 1.14 1.04 to 1.25
Child-Pugh score 0.51 0.30 to 0.90 Child-Pugh score 0.63 0.40 to 0.98
Creatinine 1.00 1.00 to 1.01    
  1. Variables used in the model were age, Child-Pugh score, Acute Physiology and Chronic Health Evaluation II score, creatinine, INR, fluid balance on day 1, hydrocortisone therapy and either the presence of intra-abdominal hypertension (mean intra-abdominal pressure ≥ 12 vs. < 12 mmHg) or abdominal hypoperfusion (mean abdominal perfusion pressure < 60 vs. ≥ 60 mmHg) on first ICU admission day. Variables with p < 0.1 on stepwise multivariate logistic regression analysis are reported in the table. APACHE, Acute Physiology and Chronic Health Evaluation; INR, international normalized ratio; RRT, renal replacement therapy.