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Table 1 Main biochemical changes in RBC storage medium and in loss of RBC deformability over the storage period [[10, 67]]

From: Age of red blood cells and transfusion in critically ill patients

Variables Length of storage
  Day 1 Days 7 Days 15 Day 42
K (mmol/L) 3.9 ± 0.6 13.6 ± 1.7 24.5 ± 2.1 46.6 ± 4.1
pH 6.8 ± 0.03 6.74 ± 0.03 6.64 ± 0.02 6.37 ± 0.04
Lactate (mmol/L) 3.6 ± 0.4 7.8 ± 0.7 17.2 ± 2.5 34.5 ± 4.4
Iron (μmol/L) 3.8 ± 0.9 6.8 ± 2.9 7.6 ± 1.6 14.2 ± 2.9
Free hemoglobin (g/L) 1.3 ± 0.5 1.5 ± 0.8 1.7 ± 0.5 3.0 ± 2.1
Percentage of irreversible deformed RBCs - 8.4 ± 1.6 14.7 ± 2.6 29.9 ± 4.0