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Table 4 Multicenter, randomized, clinical trials about blood storage in critically ill adults

From: Age of red blood cells and transfusion in critically ill patients

Authors or study name Population Sample size Case criteria Controlled criteria Outcome Status
Hebert et al.[51] ICU 57 <8 days Standard practices Composite outcome* (pilot study) Achieved
Aubron et al.[67] ICU 51 Freshest compatible available RBC Standard practices Feasibility (pilot study) Achieved
**RECESS (NCT00991341) Post cardiac surgery 1434 ≤10 days ≥21 days Change in MODS In progress
**ABLE (ISRCTN44878718) ICU 2510 <8 days Standard practices 90-day mortality In progress
**TRANSFUSE (ACTRN12612000453886) ICU excluding postcardiac surgery 5000 Freshest compatible available RBC Standard practices 90-day mortality In progress
  1. RECESS, Red Cell Storage Duration Study; ABLE, Age of Blood Evaluation; TRANSFUSE, STandaRd Issue TrANsfusion versuS Fresher red blood cell Use in intenSive carE; MODS multiorgan dysfunction score; **Indicates the trial is in progress.
  2. *Included hospital mortality, serious nosocomial infections, thrombotic events with myocardial infarction and acute ischemic stroke.