Figure 3From: Beyond intracranial pressure: optimization of cerebral blood flow, oxygen, and substrate delivery after traumatic brain injuryPbtO 2 -guided management of CPP in individual patients. Example of a patient exhibiting a linear correlation between CPP and PbtO2, which suggests impaired cerebrovascular reactivity (elevated oxygen reactivity index, ORx, > 0.7). In this case, higher CPP thresholds (>80 mmHg) are required to prevent secondary ischemia (PbtO2 < 20 mmHg). This is an example of how PbtO2 monitoring may guide CPP management and the setting of “optimal” CPP at the bedside.Back to article page