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Figure 1 | Annals of Intensive Care

Figure 1

From: Cumulative lactate and hospital mortality in ICU patients

Figure 1

Calculation of lactate area under the curve above the upper normal limit of lactate (2.2 mmol/L). The following four equations were used in computing lactate-AUC: 1) AUC A = ((½· (lactate 0 – lactate 1)) + lactate 1)) · (time 1 – time 0); 2) AUC B = ((½· (lactate 2 – lactate 1)) + lactate 1)) · (time 2 – time 1); 3) AUC C = ((lactate 2 – 2.2)2 · (time 3 – time 2)) / 2 · lactate 2; 4) AUC D = ((lactate 4 – 2.2)2 · (time 4 – time 3)) / 2 · lactate 4.

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