An observational study on rhabdomyolysis in the intensive care unit. Exploring its risk factors and main complication: acute kidney injury

Annals of Intensive Care

Table 4 Odds ratios for the development of acute kidney injury

	Models corrected for known risk factors*
		95% conf int			Area under
	OR	Lower	Upper	P value	ROC Curve
Log10 Creatine kinase	2.21	1.45	3.38	0.0002	0.759
Log10 Serum Myoglobin	7.87	4.60	13.85	< 0.0001	0.790
Log10 Urinary Myoglobin	1.61	1.21	2.13	0.0010	0.766
CK 170 - 1000 U/L**	1.42	0.84	2.45	0.1979
CK 1000 - 5000 U/L**	2.56	1.27	5.21	0.0087
CK > 5000 U/L**	5.12	1.84	14.29	0.0018

*Risk factors at baseline: mean blood pressure, creatinine, CK, sMb, uMb, PaO₂, lactate, osmolarity, SOFA, use of loop diuretics, sepsis, hours of surgery > 6, inotropic index, mechanical ventilation, trauma and muscle ischemia.
**The different CK categories are compared with reference CK < 170 U/L.