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Table 2 Outcome and monitoring data of patients

From: Daily sedative interruption versus intermittent sedation in mechanically ventilated critically ill patients: a randomized trial

Outcomes

Intermittent sedation (n = 30)

Daily interruption (n = 30)

P- value

Ventilator-free days in 28 days, days

25 (21, 27)

24 (0, 26)

0.160

ICU mortality, n (%)

7 (23)

12 (40)

0.165

Hospital mortality, n (%)

9 (30)

13 (43.3)

0.284

Delirium, n (%)

12 (40)

9 (30)

0.472

Delirium or coma-free days, days

6 (1,7)

7 (3, 7)

0.514

Median SAS

3.6 (3.4, 4.0)

3.2 (2.6, 3.7)

0.035

Percentage of time on target SAS, (%)

75 (50, 100)

63 (42, 95)

0.624

ICU length of stay, days

11 (6, 16)

8 (5, 19)

0.595

Hospital length of stay, days

22 (13, 38)

15 (9, 28)

0.099

Reintubation, n (%)

1 (3)

4 (13)

0.161

Self-extubation, n (%)

2 (7)

1 (3)

0.514

Accidental removal of catheters, n (%)

1 (3)

2 (7)

0.554

Tracheostomy, n (%)

1 (3)

1 (3)

1.000

Total drug dose per patient

   

Fentanyl, μg

300 (100, 1,520)

1,500 (520, 4,215)

0.004

Midazolam, mg

0 (0.0,0.5)

45 (0,201)

< 0.001

Propofol, mg

0 (0.0,0.0)

0 (0.0,0.0)

0.799

Haloperidol, mg

0 (0.0,0.0)

0 (0.0,0.0)

0.280