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Table 2 Outcome and monitoring data of patients

From: Daily sedative interruption versus intermittent sedation in mechanically ventilated critically ill patients: a randomized trial

Outcomes Intermittent sedation (n = 30) Daily interruption (n = 30) P- value
Ventilator-free days in 28 days, days 25 (21, 27) 24 (0, 26) 0.160
ICU mortality, n (%) 7 (23) 12 (40) 0.165
Hospital mortality, n (%) 9 (30) 13 (43.3) 0.284
Delirium, n (%) 12 (40) 9 (30) 0.472
Delirium or coma-free days, days 6 (1,7) 7 (3, 7) 0.514
Median SAS 3.6 (3.4, 4.0) 3.2 (2.6, 3.7) 0.035
Percentage of time on target SAS, (%) 75 (50, 100) 63 (42, 95) 0.624
ICU length of stay, days 11 (6, 16) 8 (5, 19) 0.595
Hospital length of stay, days 22 (13, 38) 15 (9, 28) 0.099
Reintubation, n (%) 1 (3) 4 (13) 0.161
Self-extubation, n (%) 2 (7) 1 (3) 0.514
Accidental removal of catheters, n (%) 1 (3) 2 (7) 0.554
Tracheostomy, n (%) 1 (3) 1 (3) 1.000
Total drug dose per patient    
Fentanyl, μg 300 (100, 1,520) 1,500 (520, 4,215) 0.004
Midazolam, mg 0 (0.0,0.5) 45 (0,201) < 0.001
Propofol, mg 0 (0.0,0.0) 0 (0.0,0.0) 0.799
Haloperidol, mg 0 (0.0,0.0) 0 (0.0,0.0) 0.280