Is there still a role for the lung injury score in the era of the Berlin definition ARDS?

Annals of Intensive Care

Table 2 Baseline characteristics among 550 patients with acute respiratory distress syndrome (ARDS)

Characteristic	Total cohort = 550 (%)	Survived to discharge	Died in the hospital	P-value
Characteristic	Total cohort = 550 (%)	(N = 415)	(N = 135)	P-value
Age, mean ± SD	51 ± 18	49 ± 18	56 ± 17	< 0.001
Male	322 (59%)	247 (60%)	75 (56%)	0.42
White race	469 (85%)	432 (82%)	127 (94%)	0.01
Primary ARDS risk factor^a				< 0.001
Sepsis	152 (27%)	104 (25%)	48 (36%)
Pneumonia	98 (18%)	69 (17%)	29 (21%)
Trauma	189 (34%)	165 (40%)	24 (18%)
Aspiration	73 (13%)	52 (13%)	21 (16%)
Other^b	38 (7%)	25 (6%)	13 (10%)
Non-invasive ventilation only on day of ARDS diagnosis	4 (1%)	1 (0%)	3 (2%)	0.02
Sepsis within first 72 hours of enrollment	357 (66%)	265 (64%)	97 (72%)	0.09
PaO₂/FiO₂ on the day of ARDS diagnosis, mean ± SD^c	157 ± 81	161 ± 82	145 ± 77	0.07
SpO₂/FiO₂ on the day of ARDS diagnosis, mean ± SD^d	169 ± 62	175 ± 59	151 ± 66	< 0.001
PEEP, mean ± SD	10 ± 4	10 ± 4	11 ± 4	0.003
Static compliance of the respiratory system, mean ± SD^e	34 ± 28	34 ± 27	34 ± 30	0.95
APACHE II, mean ± SD	29 ± 8	28 ± 7	32 ± 7	< 0.001
SAPS II, mean ± SD	57 ± 16	55 ± 15	63 ± 16	< 0.001

Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, ARDS acute respiratory distress syndrome, IQR interquartile range, PaO₂/FiO_2, partial pressure of arterial oxygen to the fraction of inspired oxygen, PEEP positive end-expiratory pressure, SAPS Simplified Acute Physiology Score, SD standard deviation.
Presented as N (%) unless otherwise specified.
^aPercentages not adding to 100 are due to rounding.
^bIncludes pancreatitis, near drowning, transfusion-related, and so on.
^c PaO₂/FiO₂ among 469 patients.
^dSpO₂/FiO₂ among 512 patients.
^eAmong 515 patients.