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Table 2 Baseline characteristics among 550 patients with acute respiratory distress syndrome (ARDS)

From: Is there still a role for the lung injury score in the era of the Berlin definition ARDS?

Characteristic Total cohort = 550 (%) Survived to discharge Died in the hospital P-value
(N = 415) (N = 135)
Age, mean ± SD 51 ± 18 49 ± 18 56 ± 17 < 0.001
Male 322 (59%) 247 (60%) 75 (56%) 0.42
White race 469 (85%) 432 (82%) 127 (94%) 0.01
Primary ARDS risk factora     < 0.001
  Sepsis 152 (27%) 104 (25%) 48 (36%)  
  Pneumonia 98 (18%) 69 (17%) 29 (21%)  
  Trauma 189 (34%) 165 (40%) 24 (18%)  
  Aspiration 73 (13%) 52 (13%) 21 (16%)  
  Otherb 38 (7%) 25 (6%) 13 (10%)  
Non-invasive ventilation only on day of ARDS diagnosis 4 (1%) 1 (0%) 3 (2%) 0.02
Sepsis within first 72 hours of enrollment 357 (66%) 265 (64%) 97 (72%) 0.09
PaO2/FiO2 on the day of ARDS diagnosis, mean ± SDc 157 ± 81 161 ± 82 145 ± 77 0.07
SpO2/FiO2 on the day of ARDS diagnosis, mean ± SDd 169 ± 62 175 ± 59 151 ± 66 < 0.001
PEEP, mean ± SD 10 ± 4 10 ± 4 11 ± 4 0.003
Static compliance of the respiratory system, mean ± SDe 34 ± 28 34 ± 27 34 ± 30 0.95
APACHE II, mean ± SD 29 ± 8 28 ± 7 32 ± 7 < 0.001
SAPS II, mean ± SD 57 ± 16 55 ± 15 63 ± 16 < 0.001
  1. Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, ARDS acute respiratory distress syndrome, IQR interquartile range, PaO 2 /FiO2, partial pressure of arterial oxygen to the fraction of inspired oxygen, PEEP positive end-expiratory pressure, SAPS Simplified Acute Physiology Score, SD standard deviation.
  2. Presented as N (%) unless otherwise specified.
  3. aPercentages not adding to 100 are due to rounding.
  4. bIncludes pancreatitis, near drowning, transfusion-related, and so on.
  5. c PaO2/FiO2 among 469 patients.
  6. dSpO2/FiO2 among 512 patients.
  7. eAmong 515 patients.