Association between initial prescribed minute ventilation and post-resuscitation partial pressure of arterial carbon dioxide in patients with post-cardiac arrest syndrome

Annals of Intensive Care

Table 3 Results of sensitivity analyses: multivariable logistic regression models of the association between Normocapnia (defined as partial pressure of arterial carbon dioxide 31 to 49 mmHg) on initial post-resuscitation arterial blood gas, and good neurological function (defined as Cerebral Performance Category 1 or 2) at hospital discharge

Variable	Beta	Standard error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.51	0.62	4.54	1.34	15.35	0.01
PEA/asystole initial rhythm	-0.65	0.58	0.52	0.17	1.63	0.26
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.50	0.62	4.50	1.33	15.15	0.02
CPR > 20 minutes	-0.34	0.89	0.71	0.13	4.06	0.70
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.24	0.63	3.46	1.01	11.89	0.04
Post-resuscitation shock^a	-2.16	1.14	0.11	0.01	1.08	0.05
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.36	0.63	3.89	1.14	13.26	0.03
Metabolic acidosis^b	-0.76	0.54	0.47	0.16	1.34	0.16
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.56	0.63	4.76	1.39	16.28	0.01
Age (decile)	-0.23	0.16	0.79	0.58	1.09	0.15
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.49	0.62	4.44	1.31	15.11	0.02
Charlson comorbidity index	-0.44	0.28	0.64	0.37	1.10	0.11
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.40	0.62	4.07	1.20	13.78	0.02
Pulmonary disease	-0.84	0.64	0.43	0.12	1.52	0.19
Variable	Beta	Standard Error	Odds Ratio	95% LCI	95% UCI	P-value
Normocapnia	1.41	0.62	4.11	1.21	13.93	0.02
Therapeutic hypothermia	-0.44	0.54	0.64	0.22	1.86	0.42

^aDefined as systolic blood pressure < 100 mmHg or vasopressor support required to maintain systolic blood pressure > 100 mmHg during the first 24 hours after return of spontaneous circulation; ^bDefined as a base deficit ≤ -6 during the first 24 hours after return of spontaneous circulation; CPR, cardiopulmonary resuscitation; LCI, lower confidence interval; PEA, pulseless electrical activity; UCI, upper confidence interval.