|
Age, mean (SD)
|
50.3 (17.3)
|
50.3 (16.4)
|
50.4 (19.5)
|
0.972
|
|
Male sex, n (%)
|
45 (53%)
|
31 (52%)
|
14 (58%)
|
0.755
|
|
SAPS 3 score, median (IQ)
|
52 (41.75;64)
|
48.5 (39.5;58.75)
|
60.5 (52;71.75)
|
0.002
|
|
SOFA score, median (IQ)
|
5 (2;8.25)
|
4 (2;7)
|
9 (5;11.25)
|
< 0.001
|
|
Admission due to sepsis, n (%)
|
41 (48)
|
24 (40)
|
17 (70)
|
0.020
|
|
Vasopressors at admission, n (%)
|
23 (27)
|
11 (18)
|
12 (50)
|
0.007
|
|
Need for renal replacement therapy, n (%)
|
24 (28)
|
12 (20)
|
12 (50)
|
0.013
|
|
Comorbidities, n (%)
| | | | |
|
Heart failure
|
20 (23)
|
17 (28)
|
3 (12)
|
0.209
|
|
Diabetes
|
23 (27)
|
16 (27)
|
7 (29)
|
0.974
|
|
Hypertension
|
44 (52)
|
34 (57)
|
10 (42)
|
0.316
|
|
Myocardial infarction
|
7 (8)
|
6 (10)
|
1 (4)
|
0.662
|
|
Stroke
|
10 (12)
|
5 (8)
|
5 (20)
|
0.220
|
|
Cancer
|
3 (3)
|
2 (3)
|
1 (4)
|
0.642
|
|
Rheumatic disease
|
3 (3)
|
1 (1)
|
2 (8)
|
0.402
|
|
Cirrhosis
|
4 (5)
|
2 (3)
|
2 (8)
|
0.685
|
|
Child-Pugh A
|
2 (2)
|
1 (2)
|
1 (4)
|
0.909
|
|
Child-Pugh B/C
|
2 (2)
|
1 (2)
|
1 (4)
|
0.909
|
|
Dementia
|
0 (0)
|
0 (0)
|
0 (0)
|
-
|
|
COPD
|
3 (3)
|
2 (3)
|
1 (4)
|
0.642
|
|
Chronic kidney disease
|
16 (20)
|
12 (20)
|
4 (17)
|
0.965
|
|
Creatinine, mg/dL (SD)
|
1.2 (0.81;2.6)
|
1.14 (0.79;2.17)
|
1.61 (0.87;2.85)
|
0.592
|
|
Lactate, mmol/L (IQ)
|
1.56 (1.11;2.13)
|
1.50 (1.11;1.91)
|
1.72 (1.19;3.72)
|
0.197
|
|
Albumin, g/dL
|
2.92 (0.70)
|
3.20 (0.65)
|
2.45 (0.59)
|
< 0.001
|
|
Hemoglobin, g/dL
|
11.0 (2.32)
|
11.4 (2.20)
|
10.1 (2.43)
|
0.038
|
|
Leukocyte count, units/mm3
|
11,480 (7,458;15,970)
|
11,480 (7,615;14,180)
|
11,090 (6,072;20,310)
|
0.940
|
|
Platelet count at admission, 103 units/mm3
|
184.5 (138.5;262.2)
|
192.5 (147.5;262.2)
|
156 (119.5;254.5)
|
0.149
|
|
Mean platelet volume at admission, fL
|
10.8 (10.2;11.5)
|
10.9 (10.2;11.7)
|
10.8 (10.1;11.2)
|
0.516
|
|
Platelet count at 24 hours, 103 units/mm3a
|
184 (132.5;265.5)
|
190 (143.2;273.2)
|
139 (115;204)
|
0.031
|
|
Mean platelet volume at 24 hours, fLa
|
11 (10.1;11.6)
|
11.0 (10.0;11.6)
|
11.0 (10.3;11.6)
|
0.511
|
|
Platelet count at 48 hours, 103 units/mm3b
|
188 (131;276)
|
198 (144;293.7)
|
136.5 (99.2;215.8)
|
0.040
|
|
Mean platelet volume at 48 hours, fLb
|
11.1 (10.2;11.7)
|
11.0 (10.1;11.6)
|
11.2 (10.6;11.8)
|
0.333
|
|
Platelet count at 72 hours, 103 units/mm3c
|
188 (133;263)
|
208.5 (142.5;280.8)
|
146 (96;229)
|
0.093
|
|
Mean platelet volume at 72 hours, fLc
|
11.0 (10.3;11.7)
|
10.6 (10.2;11.7)
|
11.3 (10.7;11.7)
|
0.097
|
|
ΔMPV24h,%a
|
0 (−1.68;2.41)
|
−0.81 (−1.80;1.87)
|
2.04 (0;6.01)
|
0.005
|
|
ΔPLAT24h,%a
|
−4.27 (−12.71;8.83)
|
−2.52 (−11.74;8.82)
|
−6.18 (−24.84;5.85)
|
0.032
|
