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Table 1 Characteristics of included patients

From: An increase in mean platelet volume after admission is associated with higher mortality in critically ill patients

  All patients Survivors Non-survivors P
(n = 84) (n = 60) (n = 24)
Age, mean (SD) 50.3 (17.3) 50.3 (16.4) 50.4 (19.5) 0.972
Male sex, n (%) 45 (53%) 31 (52%) 14 (58%) 0.755
SAPS 3 score, median (IQ) 52 (41.75;64) 48.5 (39.5;58.75) 60.5 (52;71.75) 0.002
SOFA score, median (IQ) 5 (2;8.25) 4 (2;7) 9 (5;11.25) < 0.001
Admission due to sepsis, n (%) 41 (48) 24 (40) 17 (70) 0.020
Vasopressors at admission, n (%) 23 (27) 11 (18) 12 (50) 0.007
Need for renal replacement therapy, n (%) 24 (28) 12 (20) 12 (50) 0.013
Comorbidities, n (%)     
Heart failure 20 (23) 17 (28) 3 (12) 0.209
Diabetes 23 (27) 16 (27) 7 (29) 0.974
Hypertension 44 (52) 34 (57) 10 (42) 0.316
Myocardial infarction 7 (8) 6 (10) 1 (4) 0.662
Stroke 10 (12) 5 (8) 5 (20) 0.220
Cancer 3 (3) 2 (3) 1 (4) 0.642
Rheumatic disease 3 (3) 1 (1) 2 (8) 0.402
Cirrhosis 4 (5) 2 (3) 2 (8) 0.685
Child-Pugh A 2 (2) 1 (2) 1 (4) 0.909
Child-Pugh B/C 2 (2) 1 (2) 1 (4) 0.909
Dementia 0 (0) 0 (0) 0 (0) -
COPD 3 (3) 2 (3) 1 (4) 0.642
Chronic kidney disease 16 (20) 12 (20) 4 (17) 0.965
Creatinine, mg/dL (SD) 1.2 (0.81;2.6) 1.14 (0.79;2.17) 1.61 (0.87;2.85) 0.592
Lactate, mmol/L (IQ) 1.56 (1.11;2.13) 1.50 (1.11;1.91) 1.72 (1.19;3.72) 0.197
Albumin, g/dL 2.92 (0.70) 3.20 (0.65) 2.45 (0.59) < 0.001
Hemoglobin, g/dL 11.0 (2.32) 11.4 (2.20) 10.1 (2.43) 0.038
Leukocyte count, units/mm3 11,480 (7,458;15,970) 11,480 (7,615;14,180) 11,090 (6,072;20,310) 0.940
Platelet count at admission, 103 units/mm3 184.5 (138.5;262.2) 192.5 (147.5;262.2) 156 (119.5;254.5) 0.149
Mean platelet volume at admission, fL 10.8 (10.2;11.5) 10.9 (10.2;11.7) 10.8 (10.1;11.2) 0.516
Platelet count at 24 hours, 103 units/mm3a 184 (132.5;265.5) 190 (143.2;273.2) 139 (115;204) 0.031
Mean platelet volume at 24 hours, fLa 11 (10.1;11.6) 11.0 (10.0;11.6) 11.0 (10.3;11.6) 0.511
Platelet count at 48 hours, 103 units/mm3b 188 (131;276) 198 (144;293.7) 136.5 (99.2;215.8) 0.040
Mean platelet volume at 48 hours, fLb 11.1 (10.2;11.7) 11.0 (10.1;11.6) 11.2 (10.6;11.8) 0.333
Platelet count at 72 hours, 103 units/mm3c 188 (133;263) 208.5 (142.5;280.8) 146 (96;229) 0.093
Mean platelet volume at 72 hours, fLc 11.0 (10.3;11.7) 10.6 (10.2;11.7) 11.3 (10.7;11.7) 0.097
ΔMPV24h,%a 0 (−1.68;2.41) −0.81 (−1.80;1.87) 2.04 (0;6.01) 0.005
ΔPLAT24h,%a −4.27 (−12.71;8.83) −2.52 (−11.74;8.82) −6.18 (−24.84;5.85) 0.032
  1. adata for 83 patients; bdata for 81 patients; cdata for 77 patients. COPD, chronic obstructive pulmonary disease; IQ, interquartile range; SAPS 3; Simplified Acute Physiology Score; SOFA score, Sequential Organ Failure Assessment score.