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Table 3 FiO 2 adjustment following ABG analysis and its effects on oxygenation measured in the next ABG

From: Self-reported attitudes versus actual practice of oxygen therapy by ICU physicians and nurses

PaO2(%)

Adjustment of FiO2(%)

Successive PaO2

[n = 61,073]

[n = 107,888]

[n = 62,222]

Higher

Unchanged

Lower

(Delta PaO2)

(Delta PaO2)

<7 kPa (1.2)

Higher (34.7)

96.6% (+5.3)

0.4%

3.0% (−0.5)

Unchanged (46.9)

87.4% (+5.6)

3.2%

9.4% (−0.6)

Lower (18.4)

95.1% (+7.9)

2.4%

2.5% (−0.9)

7 to 10 kPa (25.3)

Higher (27.9)

76.3% (+3.1)

2.7%

21.0% (−0.9)

Unchanged (56.0)

66.3% (+2.0)

4.3%

29.4% (−0.8)

Lower (16.1)

61.3% (+2.6)

3.6%

35.1% (−1.0)

>10 kPa (73.4)

Higher (10.8)

48.6% (+4.6)

2.1%

49.3% (−3.1)

Unchanged (62.0)

44.7% (+2.1)

3.1%

52.2% (−2.3)

Lower (27.2)

23.5% (+2.4)

1.7%

74.8% (−4.6)

Total (100)

-

46.3% (+2.6)

2.7%

51.0% (−2.9)

  1. Data presented as percentages of total and irrespective of adjustment of other ventilator settings (e.g., PEEP, I/E ratio). PaO2 = any recorded PaO2 stratified by self-reported ranges; successive PaO2 = PaO2 from successively registered ABG sample; Delta = mean difference between two successive ABG samples; Higher = increased FiO2 (column 2) or PaO2 (column 3), higher than previous level; unchanged = FiO2 or PaO2 equal to previous level; lower = decreased FiO2 or PaO2, lower than previous level. A total of 62,222 PaO2 measurements from 3,791 patients (57.7% of all 107,888 ABG samples) in the database is followed by an adjustment of ventilator settings, and 98.2% of PO2 measurements is followed by a successive PO2 measurement (n = 61,073) in the same patient when adjustment of FiO2 is also measured.