Duration of hemodynamic effects of crystalloids in patients with circulatory shock after initial resuscitation

Annals of Intensive Care

Table 2 Time-course of hemodynamic variables (all patients)

Variables	T0 (baseline)	T1 (30 min)	T2 (60 min)	T3 (90 min)
RAP (mmHg)	8.20 ± 3.02	10.5 ± 3.17*	9.0 ± 3.06*^,+	9.10 ± 4.00*^,+
PAOP (mmHg)	8.52 ± 3.16	10.13 ± 3.71*	8.81 ± 3.15⁺	8.67 ± 3.36⁺
MAP (mmHg)	73.70 ± 8.18	81.70 ± 9.64*	77.95 ± 10.28*	77.60 ± 13.05
HR (beats/min)	109 ± 18.48	106.15 ± 18.11	107.35 ± 19.20	107.55 ± 19.45
SvO₂ (%)	66.30 ± 9.03	69.07 ± 7.98*
Lactate (mg/dL)	3.44 (1.92 to 5.47)	3.0 (1.86 to 5.53)
Hb (g/dL)	9.59 ± 1.62	9.17 ± 1.80

RAP, right atrial pressure; PAOP, pulmonary artery occlusion pressure; MAP, mean arterial pressure; HR, heart rate; SvO₂, mixed venous oxygen saturation; Hb, hemoglobin. *p < 0.05 versus baseline, ⁺p < 0.05 versus T1. Data are expressed as means (SD) or medians (IQR 25th to 75th percentile).