When to stop septic shock resuscitation: clues from a dynamic perfusion monitoring

Annals of Intensive Care

Table 3 Evolution of microcirculatory parameters in a cohort of 31 hospital survivors

Perfusion parameters	Number of patients with altered baseline values	Baseline	2 h	6 h	24 h	pvalue^a
PPV (%)	30	69 [62 to 75]	70 [68 to 78]	71 [67 to 79]	77 [68 to 83]	0.04
MFI (score)	28	1.9 [1.5 to 2.2]	2.0 [1.6 to 2.2]	2.1 [1.8 to 2.3]	2.2 [2.0 to 2.5]	0.003
StO₂ (%)	8	72 [65 to 74]	73.5 [71 to 76]	75.5 [69 to 84]	77 [68 to 85]	NS
StO₂ recovery slope (%/s)	23	1.72 [0.6 to 2.0]	1.76 [0.7 to 2.7]	1.70 [1.2 to 2.8]	2.0 [1.6 to 3.1]	0.055

Values are expressed as median [interquartile range]. ^aComparison within group of variables was made with non-parametric trend. PPV, proportion of perfused vessels; MFI, microcirculatory flow index; PVD, perfused vessel density; StO₂, tissue oxygen saturation.