Timing of (supplemental) parenteral nutrition in critically ill patients: a systematic review

Annals of Intensive Care

Table 1 Critical appraisal of selected studies

Specification per item: Domain: critically ill adult patients on the ICU? + = yes, − = no. Determinant: parenteral nutrition? + = with PN, − = no PN. Randomization: concealed treatment allocation? + = yes, − = no; similarity subgroups in baseline characteristics? + = yes, − = no. Blinding: + = yes, +/− = partial, − = no. Standardization: + = yes, − = no. Missing data: percentage? + = <5%, +/− = 10%, − = >10%; reason? + = reason given, − = reason not given. Follow-up: percentage? + = < 5%, +/− = 10%, − = >10%; reason? + = reason given, +/− = not all reasons given, − = reason not given; ITT analysis? + = yes, − = no. ITT analysis, intention to treat analysis; x, not applicable.