Characteristics | Intervention group | Control group |
---|---|---|
N=218 | N=226 | |
Age, mean (SD) | 53.5 (16.2) | 55.5 (16.6) |
Female sex, n (%) | 91 (41.7) | 90 (39.8) |
APACHE II score, mean (SD) | 25.6 (7.9) | 26.4 (7.8) |
PaO2/FiO2, mean (SD) | 145.5 (43.5) | 149.2 (51.6) |
Set PEEP, cm H2O, mean (SD) | 11.2 (3.4) | 10.9 (3.2) |
Pplateau, cm H2O, mean (SD) | 30.4 (5.6) | 30.1 (6.1) |
PaCO2, mean (SD) | 43.0 (11.2) | 42.1 (9.5) |
pH, mean (SD) | 7.4 (0.1) | 7.4 (0.1) |
Tidal volume, ml/kg PBW, mean (SD) | 8.4 (2.1) | 8.2 (2.0) |
Minute ventilation, mean (SD) | 11.9 (3.6) | 11.9 (3.9) |
Glasgow Coma Score, mean (SD) | 6.2 (3.9) | 6.4 (4.0) |
Hepatic failure/cirrhosis, n (%) | 11 (5.1) | 8 (3.5) |
Chronic dialysis, n (%) | 22 (10.1) | 21 (9.3) |
Corticosteroids, n (%) | 52 (51.5) | 49 (48.5) |
Sedative infusions, n (%) | 166 (76.2) | 178 (78.8) |
Opioid infusions, n (%) | 150 (68.8) | 162 (71.7) |
Neuromuscular blockers, n (%) | 42 (19.3) | 39 (17.3) |