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Table 2 Characteristics of the patients included in the study

From: Multiplex PCR performed of bronchoalveolar lavage fluid increases pathogen identification rate in critically ill patients with pneumonia: a pilot study

Pneumonia

Infectious (n= 53)

Noninfectious (n= 12)

CAP = 29

HAP = 24 (with 9 VAP)

Gender (male to female ratio)

62.7%

25%

Mean age (years)

61.1 ± 16.4

55 ± 15.3

SAPS II

48.4 ± 25,1

38.8 ± 17

Immunodeficiency

24 (45.3%)

6 (50%)

HIV

8

0

Neoplasia/hematologic disease

6/4

0/2

Systemic disease

4

3

Inflammatory bowel disease

1

1

Liver transplant

1

0

Immunosuppressive therapy

14 (26.4%)

8 (66.6%)

Antineoplastic chemotherapy

7

1

Corticosteroids

5

6

Anti-TNF antibodies

0

2

Azathioprine

1

0

Previous antibiotic therapy

74%

83%

Clinical characteristics

  

Temperature <36° or >38°

28 (52.8%)

4 (33.3%)

Confusion

7 (13.2%)

3 (25%)

Shock

18 (33.9%)

4 (33.3%)

Mechanical ventilation

29 (54.7%)

8 (66.6%)

Radiologic findings

  

Multilobar infiltrates

27 (50.9%)

11 (91.6%)

Laboratory findings

  

Leucocytes >11,000/mm3

31 (58.4%)

11 (91.6%)

Leucocytes <3,000/mm3

8 (15%)

2 (15.6%)

CRP

204 ± 139

125 ± 100

PCT >10 ng/mL

7 (13.2%)

3 (25%)

Histology of BAL

  

Cells per mL

478,941 ± 530 571

202,000 ± 229,242

Polynuclear cells (%)

78.19 ± 11.03

76.81 ± 16.55

  1. CAP, community-acquired pneumonia; HAP, hospital-acquired pneumonia; VAP, ventilator-acquired pneumonia.