Pneumonia | Infectious (n= 53) | Noninfectious (n= 12) |
---|---|---|
CAP = 29 | ||
HAP = 24 (with 9 VAP) | ||
Gender (male to female ratio) | 62.7% | 25% |
Mean age (years) | 61.1 ± 16.4 | 55 ± 15.3 |
SAPS II | 48.4 ± 25,1 | 38.8 ± 17 |
Immunodeficiency | 24 (45.3%) | 6 (50%) |
HIV | 8 | 0 |
Neoplasia/hematologic disease | 6/4 | 0/2 |
Systemic disease | 4 | 3 |
Inflammatory bowel disease | 1 | 1 |
Liver transplant | 1 | 0 |
Immunosuppressive therapy | 14 (26.4%) | 8 (66.6%) |
Antineoplastic chemotherapy | 7 | 1 |
Corticosteroids | 5 | 6 |
Anti-TNF antibodies | 0 | 2 |
Azathioprine | 1 | 0 |
Previous antibiotic therapy | 74% | 83% |
Clinical characteristics | ||
Temperature <36° or >38° | 28 (52.8%) | 4 (33.3%) |
Confusion | 7 (13.2%) | 3 (25%) |
Shock | 18 (33.9%) | 4 (33.3%) |
Mechanical ventilation | 29 (54.7%) | 8 (66.6%) |
Radiologic findings | ||
Multilobar infiltrates | 27 (50.9%) | 11 (91.6%) |
Laboratory findings | ||
Leucocytes >11,000/mm3 | 31 (58.4%) | 11 (91.6%) |
Leucocytes <3,000/mm3 | 8 (15%) | 2 (15.6%) |
CRP | 204 ± 139 | 125 ± 100 |
PCT >10 ng/mL | 7 (13.2%) | 3 (25%) |
Histology of BAL | ||
Cells per mL | 478,941 ± 530 571 | 202,000 ± 229,242 |
Polynuclear cells (%) | 78.19 ± 11.03 | 76.81 ± 16.55 |