Table 6 Characteristics and comparisons of the 30 patients with HELLP associated to PPH
From: Postpartum acute renal failure: a multicenter study of risk factors in patients admitted to ICU
ARF groupn= 20 | No ARF groupn= 10 | pvalue | |
|---|---|---|---|
Baseline characteristics | |||
Age, yearsa | 32 [27 to 35] | 29 [24 to 32] | 0.1 |
Number of pregnancya | 2.5 [1 to 3] | 1.5 [1 to 3] | 0.45 |
Paritya | 2 [1 to 3] | 1 [1 to 2] | 0.45 |
Terma (weeks of gestation) | 37 [36 to 39] | 37 [32 to 38] | NA |
Twin gestation n = 3 | 2 (10) | 1 (10) | NA |
Obesity n = 8 | 6 (30) | 2 (20) | NA |
Chronic hypertension n = 2 | 2 (10) | 0 | NA |
Gestational hypertension n = 4 | 4 (20) | 0 | NA |
Gestational diabetes n = 8 | 6 (30) | 2 (20) | NA |
Antihypertensive drugs before pregnancy n = 1 | 1 (5) | 0 | NA |
Antihypertensive drugs during pregnancy n = 9 | 6 (30) | 3 (30) | NA |
SAPS II scorea | 31 [22 to 39] | 15 [12 to 23.5] | 0.01 |
Length of stay in the ICUa (day) | 5.5 [4 to 10] | 3 [2 to 4] | 0.04 |
Complications of delivery | |||
PPH secondary to HELLP n = 28 | 18 (90) | 10 (100) | 0.3 |
Postpartum HELLP secondary to PPH n = 2 | 2 (10) | 0 | NA |
Volume of bleedinga mL | 1,600 [1,050 to 2,100] | 2100 [975-3175] | 0.6 |
Hypotension n = 7 | 4 (20) | 3 (30) | 0.4 |
ISTH >3 n = 17 | 11 (55) | 6 (60) | 0.4 |
Treatments | |||
Crystalloids | |||
n = 22 | 16 (80) | 6 (60) | 0.38 |
mLa | 2,500 [1,500 to 3,000] | 2,500 [2,000 to 2,625] | 0.9 |
Artificial colloids | |||
n = 21 | 15 (75) | 6 (60) | 0.43 |
mLa | 1,000 [1,000 to 1,500] | 1,250 [500 to 1,625] | 0.8 |
Hyperoncotic albumin | |||
n = 8 | 6 (30) | 2 (20) | 0.68 |
mLa | 250 [200 to 400] | 300 [300 to 400] | 0.22 |
4% albumin | |||
n = 8 | 6 (30) | 2 (20) | 0.68 |
mLa | 750 [437 to 1,812] | 750 [500 to 750] | 0.86 |
Packed red cells | |||
n = 24 | 16 (80) | 8 (80) | NA |
mLa | 700 [450 to 1,150] | 800 [450 to 1,150] | 0.9 |
Platelets concentrates | |||
n = 14 | 9 (45) | 5 (50) | 0.8 |
n a | 1 [1 to 1.5] | 1 [1 to 2] | 0.09 |
Fresh frozen plasma | |||
n = 16 | 10 (50) | 6 (60) | 0.6 |
n a | 5 [2.7 to 6.2] | 2.5 [2 to 4.2] | 0.09 |
Fibrinogen concentrates | |||
n = 25 | 17 (85) | 8 (80) | NA |
ga | 4.5 [3 to 8] | 3 [2 to 7] | 0.23 |
Activated factor VII | |||
n = 1 | 1 (5) | 0 | NA |
Tranexamic acid | |||
n = 19 | 16 (80) | 3 (30) | 0.01 |
ga | 5.5 [3.6 to 6.7] | 5 [4 to 5] | 0.6 |
Antihypertensive drugs in ICU | |||
n = 25 | 17 (85) | 8 (80) | NA |
Diuretics | |||
n = 16 | 12 (60) | 4 (40) | 0.3 |
ACE inhibitors | |||
n = 14 | 10 (50) | 4 (40) | 0.6 |
Radio-contrast media | |||
n = 3 | 0 | 3 (30) | NA |
Aminoglycosides | |||
n = 1 | 1 (5) | 0 | NA |