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Table 1 Patient demographics

From: Failed noninvasive positive-pressure ventilation is associated with an increased risk of intubation-related complications

Characteristics Primary intubation ( n= 110) Failed NIPPV ( n= 125) p value
Mean age, years 58.1 (IQR 50 to 67) 61.2 (IQR 54 to 73) 0.13
Gender    
  Male 57% (63) 61% (76) 0.60
DACs    
  Total DACs (median) 2 (IQR 1 to 3) 2 (IQR 1 to 3) 0.83
  None 21.3% (23) 24% (30) 0.64
  Cervical immobilization 3.6% (4) 4.8% (6) 0.75
  Blood in airway 22.7% (25) 5.6% (7) <0.001
  Vomit in airway 4.6% (5) 4.8% (6) 1.00
  Facial/neck trauma 0.9% (1) 0.8% (1) 1.00
  Obesity 27.3% (30) 37.6% (47) 0.10
  Short neck 20.0 % (22) 37.6% (47) 0.004
  Large tongue 13.6% (15) 20.0% (25) 0.23
  Airway edema 13.6% (15) 4.0% (5) 0.01
  Small mandible 13.6% (15) 18.4% (23) 0.38
  Hypoxemia 39.1% (43) 20.8% (26) 0.003
  Hemodynamic instability 24.6% (27) 20% (25) 0.43
  Limited mouth opening 8.2% (9) 12% (15) 0.39
  Secretions 9.1% (10) 12.8% (16) 0.41
Illness severity    
Mean (median, IQR)    
  APACHE II 19.4 (18, IQR 14 to 24) 15.2 (14, IQR 11 to 18) <0.001
  Mortality mean/median 35.9% (29.1%) 24.3% (19%) <0.001
  SAPS II 46.9 (46.5, IQR 37 to 57) 40.1 (38, IQR 31 to 49)  
  Mortality mean/median 41.6% (38%) 29.4% (21%) <0.001
  APACHE IV 85 (85.5, IQR 64 to 102) 73 (69, IQR 57 to 90)  
  Mortality mean/median 37.4% (36.5%) 24.6% (20%)  
Hypoxemic respiratory failure 45.5% (50) 64%(80) 0.006
  Pneumonia or ARDS 31% (34) 49% (61) 0.008
  1. NIPPV, noninvasive positive-pressure ventilation; IQR, interquartile range; DACs, difficult airway characteristics; SAPS, simplified acute physiology score; APACHE, acute physiology and chronic health evaluation; ARDS, acute respiratory distress syndrome.
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