Skip to main content

Table 2 NIPPV and intubation demographics

From: Failed noninvasive positive-pressure ventilation is associated with an increased risk of intubation-related complications

Characteristics Primary intubation ( n= 110) Failed NIPPV ( n= 125) p value
Reason for NIPPV    
  Hypoxemia - 55.9% (66) -
  Hypercapnea - 25.4% (30) -
  Work of breathing - 8.5% (10) -
  Other - 10.2% (12) -
  Duration of NIPPV -   -
  Mean/median (h) - 12.3/5.8 -
Reason for intubationa    <0.001
  Airway protection 26.4% (29) 6.4% (8)  
  Respiratory failure 62.7% (69) 91.2% (114)  
  Patient control 1.8% (2) 0.8% (1)  
  Hemodynamic instability 5.5% (6) 0.8% (1)  
  Severe metabolic acidosis 3.6% (4) 0.8% (1)  
Method of intubation    0.25
  RSI 73.6% (81) 69.6% (87)  
  SED 25.5% (28) 30.4% (38)  
  OTI 0.9% (1) 0.0% (0)  
Operator PGY level    0.27
  1 12.8% (14) 7.2% (9)  
  2 21.1% (23) 16.0% (20)  
  3 14.7% (16) 12.8% (16)  
  4 21.1% (23) 29.6% (37)  
  5 16.5% (18) 24.8% (31)  
  6 11.9% (13) 8.8% (11)  
  Attending 1.8% (2) 0.8% (1)  
  1. aReason for intubation includes airway protection in which the patient is unable to protect the airway from aspiration of secretions; respiratory failure, which includes all etiology of respiratory failure; patient control which is defined as agitation, danger to self, or to facilitate evaluation/procedures; hemodynamic instability, which is defined as shock and severe metabolic acidosis.
  2. NIPPV, noninvasive positive-pressure ventilation; RSI, rapid sequence intubation; SED, sedation-only intubation; OTI, orotracheal intubation without medication; PGY postgraduate year.
\