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Table 2 Hemodynamic and echocardiographic variables in patients with acute respiratory distress syndrome according to transpulmonary bubble transit

From: Echocardiographic detection of transpulmonary bubble transit during acute respiratory distress syndrome

   Transpulmonary bubble transit  
   Absent-or-minor Moderate-to-large  
  N a ( n  = 159) ( n  = 57) p value
Hemodynamic variablesb     
Heart rate, bpm 212 96 ± 26 105 ± 24 0.02
Heart rate/respiratory rate ratio 205 3.8 ± 1.1 4.1 ± 1.1 0.15
Systolic arterial pressure, mmHg 205 112 ± 20 113 ± 22 0.94
Mean arterial pressure, mmHg 202 74 ± 13 75 ± 14 0.86
Hemodynamic supportb 216    
Norepinephrine   101 (64%) 35 (61%) 0.78
Dobutamine   6 (4%) 3 (5%) 0.63
Epinephrine   9 (6%) 4 (7%) 0.71
Echocardiographic variables     
Superior vena cava respiratory collapsibility, % 181 20 (14%) 13 (26%) 0.047
Maximum atrial septal excursion, mm 162 12 ± 4 12 ± 4 0.82
E/A ratio 171 1.2 ± 0.5 1.0 ± 0.4 0.02
LV systolic function 59 52 ± 18 57 ± 13 0.46
Cardiac index, L/min/m2 131 2.6 ± 0.9 3.3 ± 1.2 <0.01
Systolic pulmonary artery pressure, mmHg 146 33 ± 17 35 ± 20 0.78
Acute cor pulmonale, n (%) 216 35 (22%) 11 (19%) 0.56
  1. a N, number of patients in which the parameter could be assessed; bhemodynamic variables were recorded at the time of transesophageal echocardiography; PEEP, positive end-expiratory pressure; E/A ratio, ratio of early (E) over late (A) peak velocities at the mitral valve; LV, left ventricle.