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Table 1 Potential harm associated with continuous tube feed

From: Feeding critically ill patients the right ‘whey’: thinking outside of the box. A personal view

Organ system

Potential adverse effect

Muscle

Decreased skeletal muscle synthesis

Endocrine

Decreased secretion of GIP, GLP-1, peptide YY and CCK

 

Decreased insulin release

 

Insulin resistance

 

Hyperglycemia

Gastrointestinal

Hepatic steatosis

 

Hepatic inflammation

 

Enlarged non-contractile gall bladder

 

Impaired lipid absorption

 

Small bowel atrophy

 

Impaired small bowel function

 

Decreased mesenteric blood flow

Other

Multi-organ dysfunction syndrome

  1. GIP glucose-dependent insulinotropic polypeptide, GLP-1 glucagon-like peptide-1, CCK cholecystokinin