From: Long-term survival and quality of life after intensive care for patients 80 years of age or older
Planned surgery (n = 50) | Unplanned surgery (n = 213) | Medical reasons (n = 132) | Total (n = 395) | p value | |
---|---|---|---|---|---|
Age, mean ± SD | 83.5 ± 2.7 | 84.0 ± 2.7 | 83.5 ± 3.2 | 83.8 ± 2.9 | 0.217a |
Male, % | 64.0 | 60.6 | 60.6 | 61.0 | 0.889b |
Length of stay (LOS), median (IQR) | |||||
ICU-LOS | 2.0 (1.0–4.4) | 2.2 (1.0–5.0) | 1.2 (0.6–2.6) | 1.8 (0.9–3.9) | <0.001b |
Hospital LOS | 15.1 (10.2–26.2) | 12.9 (4.3–20.6) | 6.5 (2.0–14.3) | 11.3 (4.0–19.3) | <0.001b |
Ventilator support | |||||
Mechanical ventilator support, % (n) | 48.0 (24) | 69.5 (148) | 53.0 (70) | 61.3 (242) | 0.001b |
Mechanical ventilator support time, median (IQR) | 1.1 (0.4–3.7) | 1.3 (0.5–3.8) | 0.9 (0.3–2.0) | 1.2 (0.5–3.3) | 0.050b |
Non-invasive ventilator support, % (n) | 44.0 (22) | 33.8 (72) | 28.0 (37) | 29.6 (47) | 0.119b |
Non-invasive ventilator support time, median (IQR) | 1.2 (0.5–2.6) | 2.0 (0.6–3.0) | 1.0 (0.3–2.0) | 1.3 (0.4–2.5) | 0.056b |
Severity score, mean ± SD | |||||
SAPS II | 39.0 ± 13.2 (n = 47) | 44.6 ± 14.8 (n = 212) | 45.6 ± 15.6 (n = 131) | 44.3 ± 15.0 (n = 390) | 0.030a |
Max. SOFA | 6.3 ± 4.1 (n = 47) | 8.3 ± 3.6 (n = 212) | 7.5 ± 3.8 (n = 130) | 7.8 ± 3.8 (n = 389) | 0.002a |
Comorbidity | |||||
Charlson comorbidity index, mean ± SD | 3.2 ± 1.8 (n = 50) | 2.5 ± 2.0 (n = 209) | 2.5 ± 1.7 (n = 131) | 2.6 ± 1.9 (n = 390) | 0.050a |
Charlson comorbidity index (CCI) categories, % (n) | |||||
None (CCI 0) | 4.0 (2) | 13.4 (28) | 13.7 (18) | 12.3 (48) | 0.159b |
Mild (CCI 1–2) | 34.0 (17) | 43.1 (90) | 39.7 (52) | 40.8 (159) | 0.436b |
Moderate (CCI 3–4) | 46.0 (23) | 26.3 (55) | 36.6 (48) | 32.3 (126) | 0.009b |
Severe (CCI ≥5) | 16.0 (8) | 17.2 (36) | 9.9 (13) | 14.6 (57) | 0.163b |
Severe organ dysfunction, % (n) | |||||
Respiration | 68.0 (34) | 71.8 (153) | 56.8 (75) | 66.3 (262) | 0.016b |
Circulation | 38.0 (19) | 53.1 (113) | 40.9 (54) | 47.1 (186) | 0.035b |
Renal | 30.0 (15) | 28.6 (61) | 26.5 (35) | 28.1 (111) | 0.868b |
CNS | 20.0 (10) | 23.5 (50) | 32.6 (43) | 26.1 (103) | 0.100b |
Coagulation | 16.0 (8) | 8.5 (18) | 9.8 (13) | 9.9 (39) | 0.273b |
Liver | 2.0 (1) | 0.0 (0) | 3.0 (4) | 1.3 (5) | 0.034d |
Survival, % (n) | |||||
ICU | 90.0 (45) | 74.2 (158) | 73.5 (97) | 75.9 (300) | 0.045b |
Hospital | 84.0 (42) | 54.9 (117) | 57.6 (76) | 59.5 (235) | 0.001b |
30 days | 86.0 (43) | 51.2 (109) | 54.5 (72) | 56.7 (224) | <0.001b |
90 days | 82.0 (41) | 44.6 (95) | 50.8 (67) | 51.4 (203) | <0.001b |
180 days | 74.0 (37) | 40.4 (86) | 47.7 (63) | 47.1 (186) | <0.001b |
1 year | 68.0 (34) | 37.1 (79) | 40.2 (53) | 42.0 (166) | <0.001b |
2 years | 59.9 (28) | 33.1 (64) | 33.6 (39) | 36.6 (130) | 0.001b |
3 years | 48.4 (15) | 27.8 (50) | 29.9 (32) | 31.2 (96) | 0.088b |
5 years | 32.8 (7) | 18.6 (28) | 23.7 (22) | 22.2 (55) | 0.290b |
Diagnostic groups, % (n) | |||||
Respiratory failure | 44.0 (22) | 24.4 (52) | 28.0 (37) | 28.1 (111) | 0.021b |
Circulatory failure | 8.0 (4) | 8.5 (18) | 7.6 (10) | 8.1 (32) | 0.959b |
Combined respiratory and circulatory failure | 8.0 (4) | 12.7 (27) | 7.6 (10) | 10.4 (41) | 0.270b |
Neurologic failure | 2.0 (1) | 7.0 (15) | 18.2 (24) | 10.1 (40) | <0.001b |
Isolated head injury | 0.0 (0) | 1.9 (4) | 4.5 (6) | 2.5 (10) | 0.165d |
Sepsis | 4.0 (2) | 8.9 (19) | 10.6 (14) | 8.9 (35) | 0.308d |
Gastroenterological failure | 0 (0) | 5.6 (12) | 5.3 (7) | 4.8 (19) | 0.276d |
Multiple organ failure | 4.0 (2) | 7.5 (16) | 3.0 (4) | 5.6 (22) | 0.205d |
Multitrauma without head injury | 0.0 (0) | 5.6 (12) | 2.3 (3) | 3.8 (15) | 0.107d |
Multitrauma with head injury | 0.0 (0) | 2.3 (5) | 3.0 (4) | 2.3 (9) | 0.638d |
Planned surgery | 18.0 (9) | 1.4 (3) | 0.8 (1) | 3.3 (13) | <0.001d |
Acute operation | 2.0 (1) | 10.3 (22) | 2.3 (3) | 6.6 (26) | 0.004d |
Unspecified | 10.0 (5) | 3.8 (8) | 6.8 (9) | 5.6 (22) | 0.150d |
SMR (95 % CI) | 0.55 (0.28–1.11) (n = 47) | 1.15 (0.94–1.40) (n = 212) | 1.05 (0.81–1.37) (n = 131) | 1.06 (0.90–1.23) (n = 390) |