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Table 2 Evolution of the hemodynamic characteristics during the study

From: Right over left ventricular end-diastolic area relevance to predict hemodynamic intolerance of high-frequency oscillatory ventilation in patients with severe ARDS

  CMVpre HFOV connection H1 HFOV H3 HFOV
Concerned patients number 24 24 23 19
Heart rate (beats/min) 102 ± 22 102 ± 23 102 ± 23 102 ± 24
Systolic arterial pressure (mmHg) 120 ± 18 119 ± 23 119 ± 19 116 ± 17
Diastolic arterial pressure (mmHg) 62 ± 11 63 ± 12 65 ± 11 62 ± 11
Mean arterial pressure (mmHg) 81 ± 11 81 ± 13 80 ± 14 80 ± 12
Pulse pressure (mmHg) 57 ± 13 56 ± 17 54 ± 17 54 ± 13
Cardiac index (L min−1 m−2) (TPTD) 3.7 ± 1.1b,c,d 3.3 ± 1.3a 3.3 ± 1.2a 3.1 ± 1.1a
SVI (mL min−1 m−2) (TPTD) 36 ± 11b,c,d 33 ± 14a 33 ± 14a 32 ± 14a
GEDI (mL min−1 m−2) (TPTD) 680 ± 140b,c,d 634 ± 134a 646 ± 126a 625 ± 112a
CFI (min−1) (TPTD) 5.5 ± 1.8b,c,d 5.2 ± 1.9a 5.0 ± 1.8a 5.0 ± 1.5a
LVEF (%) (TTE) 53 ± 16b,c,d 50 ± 17a 49 ± 15a 49 ± 13a
RVEDA/LVEDA ratio (TTE) 0.61 ± 0.15b,c,d 0.70 ± 0.18a 0.72 ± 0.18a 0.67 ± 0.14a
RVEDA/LVEDA ratio >0.6 [n (%)] 11 (46)b,c 17 (71)a,d 17 (74)a,d 10 (53)b,c
ACP echocardiographic pattern [n (%)] 5 (21)b,c 11 (46)a,d 10 (43)a,d 6 (32)b,c
LVOT VTI (cm) (TTE) 17 ± 5b,c,d 14 ± 5a 14 ± 5a 14 ± 5a
E-wave (cm s−1) (TTE) 90 ± 23c 86 ± 20c 80 ± 21a,b,d 91 ± 22c
A-wave (cm s−1) (TTE) 57 ± 16 58 ± 12 54 ± 12 57 ± 15
E′ (cm s−1) (TTE) 14 ± 5 14 ± 5 14 ± 4 15 ± 5
DTE (ms) (TTE) 207 ± 51 204 ± 44 213 ± 38 205 ± 46
E/A (TTE) 1.8 ± 0.5b,c 1.6 ± 0.6a 1.6 ± 0.5a 1.8 ± 0.7b,c
E/E′ (TTE) 8.3 ± 2.9 8.4 ± 2.9 7.4 ± 3.6 8.0 ± 3.0
Norepinephrine (μg kg−1 min−1) 0.59 ± 0.78 0.59 ± 0.78 0.58 ± 0.78 0.53 ± 0.69
  1. Results are given as mean ± SD
  2. CMV conventional mechanical ventilation, HFOV high frequency oscillation ventilation, TPTD transpulmonary thermodilution, SVI stroke volume index, GEDI global end diastolic index, CFI cardiac function index, LVEF left ventricular ejection fraction, TTE transthoracic echocardiography, LVEDA left ventricular end diastolic area, RVEDA right ventricular end diastolic area, LVOT VTI velocity–time integral in the left ventricular outflow tract, DTE E-wave deceleration time
  3. a p < 0.05 for all data as compared to CMVpre
  4. b p < 0.05 for all data as compared to HFOV Connection
  5. c p < 0.05 for all data as compared to H1 HFOV
  6. d p < 0.05 for all data as compared to H3 HFOV