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Table 2 Patient’s characteristics according to hospital survival status

From: Acute respiratory failure in patients with hematological malignancies: outcomes according to initial ventilation strategy. A groupe de recherche respiratoire en réanimation onco-hématologique (Grrr-OH) study

Variables Alive at hospital discharge (n = 257) Died before hospital discharge (n = 123) p
Baseline characteristics
 Age (year) m, [IQR] 60 [50–68] 60 [49.5–68.5] 0.91
 Gender male (%) 108 (42) 51 (41) 1
 Underlying malignancy    0.61
  Myeloid disease 92 (35.8) 49 (39.8)  
  Lymphoid disease 114 (44.4) 48 (39)  
  Other 52 (19.8) 26 (21.1)  
 Disease status at ICU admission    0.93
  Newly diagnosed 83 (32.4) 32 (26.2)  
  Remission 68 (26.6) 31 (25.4)  
  No remission 104 (40.6) 55 (45.1)  
 Allogeneic stem cell transplantation 37 (14.4) 37 (30.3) 0.0005
 Performance status >2 (severely disabled or bedridden) 39 (14.8) 34 (27.6) 0.005
 Charlson comorbidity score 4 [2–5] 3 [3–5] 0.9
 Time (days) from hospital to ICU admission 3 [0–16] 12 [2–24.2] <0.001
 Admission from emergency department 72 (28) 18 (14.6) 0.004
 Neutropenia at ICU admission 65 (25.3) 47 (38.2) 0.01
 ARF etiology    0.49
  Infection 115 (44.7) 46 (37.4)  
  Cardiogenic edema 29 (11.3) 14 (11.4)  
  Malignant Infiltration 40 (15.6) 25 (20.3)  
  Othera 73 (28.4) 38 (30.9)  
 Maximum respiratory rate at day 1 (/min) 32 [26–37] 33.5 [29–40] 0.026
 Noninvasive ventilation at day 1 or 2 80 (31.1) 62 (50.4) 0.0004
 Shock at day 1 44 (17.1) 19 (15.4) 0.77
 Acute kidney injury at day 1 44 (17.1) 6 [4–8] 0.77
 SOFA score at day 1 > 7 44 (18) 37 (33) 0.003
Outcome
 Intubation throughout the ICU stay 32 (12.4) 62 (50.4) <0.001
 Time from admission to intubation 4 [2–5] 3 [2–5] 0.77
 ICU length of stay 5 [3–7] 7 [3–15] <0.001
 ICU-acquired infection 17 (7) 31 (25) <0.001
  1. All data are presented as medians [25th–75th percentiles] for quantitative variables and frequencies (percentage) for qualitative variables. Comparisons between the two groups were performed with Chi-square test for qualitative value and Wilcoxon test for quantitative value
  2. iMV invasive mechanical ventilation, SOFA score Sequential Organ Failure Assessment score
  3. aOther included undetermined diagnosis (n = 94, 84 %)