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Table 2 Patient’s characteristics according to hospital survival status

From: Acute respiratory failure in patients with hematological malignancies: outcomes according to initial ventilation strategy. A groupe de recherche respiratoire en réanimation onco-hématologique (Grrr-OH) study

Variables

Alive at hospital discharge (n = 257)

Died before hospital discharge (n = 123)

p

Baseline characteristics

 Age (year) m, [IQR]

60 [50–68]

60 [49.5–68.5]

0.91

 Gender male (%)

108 (42)

51 (41)

1

 Underlying malignancy

  

0.61

  Myeloid disease

92 (35.8)

49 (39.8)

 

  Lymphoid disease

114 (44.4)

48 (39)

 

  Other

52 (19.8)

26 (21.1)

 

 Disease status at ICU admission

  

0.93

  Newly diagnosed

83 (32.4)

32 (26.2)

 

  Remission

68 (26.6)

31 (25.4)

 

  No remission

104 (40.6)

55 (45.1)

 

 Allogeneic stem cell transplantation

37 (14.4)

37 (30.3)

0.0005

 Performance status >2 (severely disabled or bedridden)

39 (14.8)

34 (27.6)

0.005

 Charlson comorbidity score

4 [2–5]

3 [3–5]

0.9

 Time (days) from hospital to ICU admission

3 [0–16]

12 [2–24.2]

<0.001

 Admission from emergency department

72 (28)

18 (14.6)

0.004

 Neutropenia at ICU admission

65 (25.3)

47 (38.2)

0.01

 ARF etiology

  

0.49

  Infection

115 (44.7)

46 (37.4)

 

  Cardiogenic edema

29 (11.3)

14 (11.4)

 

  Malignant Infiltration

40 (15.6)

25 (20.3)

 

  Othera

73 (28.4)

38 (30.9)

 

 Maximum respiratory rate at day 1 (/min)

32 [26–37]

33.5 [29–40]

0.026

 Noninvasive ventilation at day 1 or 2

80 (31.1)

62 (50.4)

0.0004

 Shock at day 1

44 (17.1)

19 (15.4)

0.77

 Acute kidney injury at day 1

44 (17.1)

6 [4–8]

0.77

 SOFA score at day 1 > 7

44 (18)

37 (33)

0.003

Outcome

 Intubation throughout the ICU stay

32 (12.4)

62 (50.4)

<0.001

 Time from admission to intubation

4 [2–5]

3 [2–5]

0.77

 ICU length of stay

5 [3–7]

7 [3–15]

<0.001

 ICU-acquired infection

17 (7)

31 (25)

<0.001

  1. All data are presented as medians [25th–75th percentiles] for quantitative variables and frequencies (percentage) for qualitative variables. Comparisons between the two groups were performed with Chi-square test for qualitative value and Wilcoxon test for quantitative value
  2. iMV invasive mechanical ventilation, SOFA score Sequential Organ Failure Assessment score
  3. aOther included undetermined diagnosis (n = 94, 84 %)