Variables | Alive at hospital discharge (n = 257) | Died before hospital discharge (n = 123) | p |
---|---|---|---|
Baseline characteristics | |||
Age (year) m, [IQR] | 60 [50–68] | 60 [49.5–68.5] | 0.91 |
Gender male (%) | 108 (42) | 51 (41) | 1 |
Underlying malignancy | 0.61 | ||
Myeloid disease | 92 (35.8) | 49 (39.8) | |
Lymphoid disease | 114 (44.4) | 48 (39) | |
Other | 52 (19.8) | 26 (21.1) | |
Disease status at ICU admission | 0.93 | ||
Newly diagnosed | 83 (32.4) | 32 (26.2) | |
Remission | 68 (26.6) | 31 (25.4) | |
No remission | 104 (40.6) | 55 (45.1) | |
Allogeneic stem cell transplantation | 37 (14.4) | 37 (30.3) | 0.0005 |
Performance status >2 (severely disabled or bedridden) | 39 (14.8) | 34 (27.6) | 0.005 |
Charlson comorbidity score | 4 [2–5] | 3 [3–5] | 0.9 |
Time (days) from hospital to ICU admission | 3 [0–16] | 12 [2–24.2] | <0.001 |
Admission from emergency department | 72 (28) | 18 (14.6) | 0.004 |
Neutropenia at ICU admission | 65 (25.3) | 47 (38.2) | 0.01 |
ARF etiology | 0.49 | ||
Infection | 115 (44.7) | 46 (37.4) | |
Cardiogenic edema | 29 (11.3) | 14 (11.4) | |
Malignant Infiltration | 40 (15.6) | 25 (20.3) | |
Othera | 73 (28.4) | 38 (30.9) | |
Maximum respiratory rate at day 1 (/min) | 32 [26–37] | 33.5 [29–40] | 0.026 |
Noninvasive ventilation at day 1 or 2 | 80 (31.1) | 62 (50.4) | 0.0004 |
Shock at day 1 | 44 (17.1) | 19 (15.4) | 0.77 |
Acute kidney injury at day 1 | 44 (17.1) | 6 [4–8] | 0.77 |
SOFA score at day 1 > 7 | 44 (18) | 37 (33) | 0.003 |
Outcome | |||
Intubation throughout the ICU stay | 32 (12.4) | 62 (50.4) | <0.001 |
Time from admission to intubation | 4 [2–5] | 3 [2–5] | 0.77 |
ICU length of stay | 5 [3–7] | 7 [3–15] | <0.001 |
ICU-acquired infection | 17 (7) | 31 (25) | <0.001 |