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Annals of Intensive Care

Table 3 Characteristics of patients matched based on the propensity score

From: Acute respiratory failure in patients with hematological malignancies: outcomes according to initial ventilation strategy. A groupe de recherche respiratoire en réanimation onco-hématologique (Grrr-OH) study

Variables Oxygen therapy (n = 55) NIV therapy (n = 55) Std diff
Baseline characteristics
 Age (year) m, [IQR] 60 [47–67] 61 [49.5–68] 0.05
 Gender male (%) 23 (41.8) 20 (36.6) 0.11
 Underlying malignancy
  Myeloid disease 27 (49) 22 (40) 0.18
  Lymphoid disease 18 (32.7) 19 (34.5) 0.04
  Other 10 (18.1) 14 (25.4) 0.17
 Remission 16 (29) 18 (32.7) 0.08
 Allogeneic stem cell transplantation 10 (18.8) 10 (18.8) 0
 Performance status >2 (severely disabled or bedridden) 12 (21.8) 11 (20) 0.04
 Charlson comorbidity score 4 [3–6] 4 [3–5] 0.01
 Time (days) from hospital to ICU admission 4 [0–15] 6 [0–13.5] 0.02
 Admission from emergency department 39 (71) 40 (72.7) 0.04
 Neutropenia at ICU admission 39 (71) 37 (67.3) 0.08
 ARF etiology
  Infection 20 (36.4) 20 (36.4) 0
  Cardiogenic edema 10 (18.2) 8 (14.5) 0.09
  Malignant Infiltration 13 (23.6) 12 (21.8) 0.04
  Othera 12 (21.8) 15 (27.3) 0.13
 Maximum respiratory rate at day 1/min 33 [26.5–38.5] 32 [29–41] 0.14
 Shock at day 1 9 (16.4) 9 (16.4) 0
 Acute kidney injury at day 1 9 (16.4) 9 (16.4) 0
 SOFA score at day 1 > 7 15 (27.3) 15 (27.3) 0
 Do not intubate order day 1 or day 2 0 (0) 2 (3.6) 0.27
VNI parameters
 Number of trial/day (day 1)   3 (2–5)  
 Number of trial/day (day 2)   3.5 (1–5.2)  
 Length of NIV (hours) (day 1)   6.2 (3–9)  
 Length of NIV (hours) (day 2)   5.5 (3–9)  
 Respiratory rate under NIV at day 1   26.5 (21.5–32.5)  
 Pressure support day 1 (cm H2O)   10 (8–13)  
 Pressure support day 2 (cm H2O)   11.5 (8.5–14)  
 PEEP at day 1 (cm H2O)   6 (5–7)  
 PEEP at day 2 (cm H2O)   5 (5–7)  
Outcome
 Intubation throughout the ICU stay 14 (25.4) 16 (29.1)  
 Time from admission to intubation 4 [2–6] 3 [2–5]  
 Length of ICU stay 5 [3–11] 6 [4–14]  
 ICU-acquired infection 5 (9) 6 (11)  
 Hospital mortality 11 (20) 15 (27.3)  
 Mortality of intubated patients 5/14 (36) 7/16 (44)  
  1. All data are presented as medians [25th–75th percentiles] for quantitative variables and frequencies (percentage) for qualitative variables
  2. Matching criteria were based on baseline characteristics known to be linked to the mortality or with a standardized difference above 0.1
  3. aOther included undetermined diagnosis
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