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Table 3 Characteristics of patients matched based on the propensity score

From: Acute respiratory failure in patients with hematological malignancies: outcomes according to initial ventilation strategy. A groupe de recherche respiratoire en réanimation onco-hématologique (Grrr-OH) study

Variables

Oxygen therapy (n = 55)

NIV therapy (n = 55)

Std diff

Baseline characteristics

 Age (year) m, [IQR]

60 [47–67]

61 [49.5–68]

0.05

 Gender male (%)

23 (41.8)

20 (36.6)

0.11

 Underlying malignancy

  Myeloid disease

27 (49)

22 (40)

0.18

  Lymphoid disease

18 (32.7)

19 (34.5)

0.04

  Other

10 (18.1)

14 (25.4)

0.17

 Remission

16 (29)

18 (32.7)

0.08

 Allogeneic stem cell transplantation

10 (18.8)

10 (18.8)

0

 Performance status >2 (severely disabled or bedridden)

12 (21.8)

11 (20)

0.04

 Charlson comorbidity score

4 [3–6]

4 [3–5]

0.01

 Time (days) from hospital to ICU admission

4 [0–15]

6 [0–13.5]

0.02

 Admission from emergency department

39 (71)

40 (72.7)

0.04

 Neutropenia at ICU admission

39 (71)

37 (67.3)

0.08

 ARF etiology

  Infection

20 (36.4)

20 (36.4)

0

  Cardiogenic edema

10 (18.2)

8 (14.5)

0.09

  Malignant Infiltration

13 (23.6)

12 (21.8)

0.04

  Othera

12 (21.8)

15 (27.3)

0.13

 Maximum respiratory rate at day 1/min

33 [26.5–38.5]

32 [29–41]

0.14

 Shock at day 1

9 (16.4)

9 (16.4)

0

 Acute kidney injury at day 1

9 (16.4)

9 (16.4)

0

 SOFA score at day 1 > 7

15 (27.3)

15 (27.3)

0

 Do not intubate order day 1 or day 2

0 (0)

2 (3.6)

0.27

VNI parameters

 Number of trial/day (day 1)

 

3 (2–5)

 

 Number of trial/day (day 2)

 

3.5 (1–5.2)

 

 Length of NIV (hours) (day 1)

 

6.2 (3–9)

 

 Length of NIV (hours) (day 2)

 

5.5 (3–9)

 

 Respiratory rate under NIV at day 1

 

26.5 (21.5–32.5)

 

 Pressure support day 1 (cm H2O)

 

10 (8–13)

 

 Pressure support day 2 (cm H2O)

 

11.5 (8.5–14)

 

 PEEP at day 1 (cm H2O)

 

6 (5–7)

 

 PEEP at day 2 (cm H2O)

 

5 (5–7)

 

Outcome

 Intubation throughout the ICU stay

14 (25.4)

16 (29.1)

 

 Time from admission to intubation

4 [2–6]

3 [2–5]

 

 Length of ICU stay

5 [3–11]

6 [4–14]

 

 ICU-acquired infection

5 (9)

6 (11)

 

 Hospital mortality

11 (20)

15 (27.3)

 

 Mortality of intubated patients

5/14 (36)

7/16 (44)

 
  1. All data are presented as medians [25th–75th percentiles] for quantitative variables and frequencies (percentage) for qualitative variables
  2. Matching criteria were based on baseline characteristics known to be linked to the mortality or with a standardized difference above 0.1
  3. aOther included undetermined diagnosis