Table 3 Insulin metrics
Patients who did not receive bolus infusion of hydrocortisone (N = 5447) | Patients who received infusion of hydrocortisone (N = 962) | P value | Total cohort (N = 6409) | |
|---|---|---|---|---|
Patients receiving insulin infusion [no (%)] | 3693 (67.8) | 875 (91.0) | <0.001 | 4568 (71.3) |
Patients receiving boluses of insulin infusion [no (%)] | 490 (9.0) | 248 (25.8) | <0.001 | 738 (11.5) |
Number of insulin rate adjustments (median [IQR]) | 3 [0–8] | 17 [6–35] | <0.001 | 4 [0–12] |
Median number of insulin rates per day (median [IQR]) | 1 [0–2] | 2 [1–3] | <0.001 | 1 [0–2] |
Median number of insulin rates per day with hydrocortisone (median [IQR]) | 3 [1–4] | |||
Median number of insulin rates per day without hydrocortisone (median [IQR]) | 1 [0–2] | |||
Patients in insulin infusion rate variability category: | ||||
No insulin infusion rate variability | 2494 (45.8) | 136 (14.1) | 2630 (41.0) | |
Small insulin infusion rate variability | 887 (16.3) | 111 (11.5) | 998 (15.6) | |
Moderate insulin infusion rate variability | 1104 (20.3) | 260 (27.0) | 1364 (21.3) | |
High insulin infusion rate variability | 962 (17.7) | 455 (47.3) | 1417 (22.1) | |
Standard deviation of insulin rate (IU/h, median [IQR]) | 0.6 [0–1.3] | 1.6 [0.8–6.2] | <0.001 | 0.7 [0–1.6] |