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Table 3 Patient characteristics during ICU stay

From: Continuous control of tracheal cuff pressure for VAP prevention: a collaborative meta-analysis of individual participant data

 

Continuous control of P cuff

 

Yes (n = 263)

No (n = 280)

p value

SOFA score at randomization

4 (1, 7)

4 (2, 6)

0.538

Subglottic secretion drainage

53 (20)

65 (23)

0.447

Antimicrobial treatment

237 (90)

260 (93)

0.321

MV duration before randomization

0 (0, 1)

0 (0, 1)

0.531

Sucralfate

42 (16)

45 (16)

>0.999

Proton-pump inhibitor

182 (69)

180 (64)

0.732

H2 receptor antagonists

31 (12)

47 (17)

0.124

Reintubation

41 (15)

30 (11)

0.120

Mean P cuff

25 (24, 26)

22 (21, 24)

<0.001

Underinflation of P cuff

2 (1)

118 (42)

<0.001

% P cuff measurements <20 cmH2O

0 (0,0)

16 (0, 18)

<0.001

Overinflation of P cuff

8 (3)

82 (29)

<0.001

Mean PEEP (cmH2O)

5 (5, 5)

5 (5, 5)

0.358

Sedation

235 (89)

253 (90)

0.806

Ramsay score

4 (3, 4)

4 (3, 4)

0.432

HOB elevation (°)

37 (30, 40)

35 (30, 40)

0.508

Paralytic agent use

22 (8)

32 (11)

0.315

Red blood cell transfusion

77 (29)

73 (26)

0.359

Enteral nutrition

178 (68)

195 (70)

0.689

Tracheostomy

49 (19)

41 (15)

0.257

  1. Data are number (%), or median (IQR)
  2. SOFA sequential organ failure assessment, MV mechanical ventilation, P cuff cuff pressure, PEEP positive end expiratory pressure, HOB head of bed