Table 3 Characteristics of the 97 ICU-acquired severe bleeding events in 40 patients
Variable | ICU-acquired severe bleeding events (n = 97) |
|---|---|
WHO bleeding classification | |
Grade 3 | 64 (66 %) |
Grade 4 | 33 (34 %) |
Timing of bleeding | |
Time between admission and bleeding (days) | 4 (1–9.5) |
Sites of bleeding | |
Digestive | 32 (33 %) |
Pulmonary | 22 (22.7 %) |
Site of invasive procedure | 13 (13.4 %) |
Central nervous system | 5 (5.1 %) |
Urinary | 8 (8.2 %) |
Others | 17 (17.5 %) |
Platelet count at the time of bleeding (×109/L) | |
≤10 | 18 (18.6 %) |
11–20 | 35 (36.1 %) |
21–50 | 37 (38.1 %) |
51–100 | 7 (7.2 %) |
Urea level at the time of bleeding (mmol/L) | 13.7 (9.1–19.8) |
Prothrombin time at the time of bleeding (%) | 56 (43.5–70.2) |
Concurrent anticoagulant and/or antiplatelet treatment | 8 (8.2 %) |
Preventive anticoagulant treatment | 5 (5.1 %) |
Curative anticoagulant treatment | 2 (2.1 %) |
Antiplatelet agent | 2 (2.1 %) |
Activated protein C | 1 (1 %) |