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Table 3 Characteristics of the 97 ICU-acquired severe bleeding events in 40 patients

From: Platelet transfusions in cancer patients with hypoproliferative thrombocytopenia in the intensive care unit

Variable ICU-acquired severe bleeding events (n = 97)
WHO bleeding classification
 Grade 3 64 (66 %)
 Grade 4 33 (34 %)
Timing of bleeding
 Time between admission and bleeding (days) 4 (1–9.5)
Sites of bleeding
 Digestive 32 (33 %)
 Pulmonary 22 (22.7 %)
 Site of invasive procedure 13 (13.4 %)
 Central nervous system 5 (5.1 %)
 Urinary 8 (8.2 %)
 Others 17 (17.5 %)
Platelet count at the time of bleeding (×109/L)
 ≤10 18 (18.6 %)
 11–20 35 (36.1 %)
 21–50 37 (38.1 %)
 51–100 7 (7.2 %)
Urea level at the time of bleeding (mmol/L) 13.7 (9.1–19.8)
Prothrombin time at the time of bleeding (%) 56 (43.5–70.2)
Concurrent anticoagulant and/or antiplatelet treatment 8 (8.2 %)
 Preventive anticoagulant treatment 5 (5.1 %)
 Curative anticoagulant treatment 2 (2.1 %)
 Antiplatelet agent 2 (2.1 %)
 Activated protein C 1 (1 %)
  1. Variables are expressed as median (interquartile range) or number (percentage)
  2. ICU intensive care unit, WHO World Health Organization